PDB entry 5igk

View 5igk on RCSB PDB site
Description: Crystal structure of the first bromodomain of human BRD4 in complex with bromosporine (BSP)
Class: transcription
Keywords: transcription, post translational modifications, BET family, Structural Genomics, Structural Genomics Consortium, SGC
Deposited on 2016-02-28, released 2016-10-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-11-02, with a file datestamp of 2016-10-28.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Bromodomain-containing protein 4
  Species: Homo sapiens [TaxId:9606]
  Gene: BRD4, HUNK1
  Database cross-references and differences (RAF-indexed):
  • Uniprot O60885 (2-126)
    • expression tag (0-1)
  Domains in SCOPe 2.07: d5igka1, d5igka2
• Heterogens: EDO, BMF, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >5igkA (A:)
  smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
  ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
  nelptee