PDB entry 5if8
View 5if8 on RCSB PDB site
Description: Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-2643 5-[(4-chlorophenyl)methyl]-1,3,4-oxadiazol-2-amine
Class: viral protein
Keywords: NIAID, structural genomics, flu, fragment screening, STD NMR, Seattle Structural Genomics Center for Infectious Disease, SSGCID, VIRAL PROTEIN
Deposited on
2016-02-25, released
2017-02-22
The last revision prior to the SCOPe 2.06 freeze date was dated
2017-02-22, with a file datestamp of
2017-02-17.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.25
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Polymerase acidic protein
Species: Influenza A virus (strain A/Wilson-Smith/1933 H1N1) [TaxId:381518]
Gene: PA
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d5if8a_ - Heterogens: 6AX, DMS, CL, EDO, GOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5if8A (A:)
gnariepflkstprplrlpdgppcsqrskfllmdalklsiedpshegegiplydaikcmr
tffgwkepnvvkphekginpnyllswkqvlaelqdieneekiprtknmkktsqlkwalge
nmapekvdfddckdvgdlkqydsdepelrslaswiqnefnkaceltdsswieldeigeda
apiehiasmrrnyftaevshcrateyimkgvyintallnascaamddfqlipmiskcrtk
egrrktnlygfiikgrshlrndtdvvnfvsmefsltdprlephkwekycvlevgdmllrs
aighvsrpmflyvrtngtskikmkwgmemrrcllqslqqiesmieaessvkekdmtkeff
enksetwpvgespkgveegsigkvcrtllaksvfnslyaspqlegfsaesrklllivqal
rdnlepgtfdlgglyeaieeclindpwvllnaswfnsflthalr
Sequence, based on observed residues (ATOM records): (download)
>5if8A (A:)
prplrlpdgppcsqrskfllmdalklsiedgiplydaikcmrtffgwkepnvvkphekgi
npnyllswkqvlaelqdieneekiprtknmkktsqlkwalgeelrslaswiqnefnkace
ltdsswieldeigedaapiehiasmrrnyftaevshcrateyimkgvyintallnascaa
mddfqlipmiskcrtkegrrktnlygfiikgrshlrndtdvvnfvsmefsltdprlephk
wekycvlevgdmllrsaighvsrpmflyvrtngtskikmkwgmemrrcllqslqqiesmi
eaessvkekdmtkeffenkspkgveegsigkvcrtllaksvfnslyaspqlegfsaesrk
lllivqalrdnlgglyeaieeclindpwvllnaswfnsflth