PDB entry 5i8u

View 5i8u on RCSB PDB site
Description: Crystal Structure of the RV1700 (MT ADPRASE) E142Q mutant
Class: hydrolase
Keywords: NUDIX, nudix hydrolase, ADP-ribose hydrolase, ADPRase, ADPr hydrolase, HYDROLASE
Deposited on 2016-02-19, released 2016-10-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-12-21, with a file datestamp of 2016-12-16.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ADP-ribose pyrophosphatase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: TBPG_001531
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A045KHE5 (Start-206)
      • engineered mutation (141)
    Domains in SCOPe 2.08: d5i8ua_
  • Chain 'B':
    Compound: ADP-ribose pyrophosphatase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: TBPG_001531
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A045KHE5 (Start-206)
      • engineered mutation (141)
    Domains in SCOPe 2.08: d5i8ub_
  • Chain 'C':
    Compound: ADP-ribose pyrophosphatase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: TBPG_001531
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A045KHE5 (Start-206)
      • engineered mutation (141)
    Domains in SCOPe 2.08: d5i8uc_
  • Chain 'D':
    Compound: ADP-ribose pyrophosphatase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: TBPG_001531
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5i8ud_
  • Chain 'E':
    Compound: ADP-ribose pyrophosphatase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: TBPG_001531
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5i8ue_
  • Chain 'F':
    Compound: ADP-ribose pyrophosphatase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: TBPG_001531
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5i8uf_
  • Chain 'G':
    Compound: ADP-ribose pyrophosphatase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: TBPG_001531
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5i8ug_
  • Heterogens: SO4, FMT, PEG, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5i8uA (A:)
maehdfetissetlhtgaifalrrdqvrmpgggivtrevvehfgavaivamddngnipmv
yqyrhtygrrlwelpaglldvagepphltaarelreevglqastwqvlvdldtapgfsde
svrvylatglrevgrpeahheqadmtmgwypiaeaarrvlrgeivnsiaiagvlavhavt
tgfaqprpldtewidrptafaarraer

    Sequence, based on observed residues (ATOM records): (download) 
    >5i8uA (A:)
dfetissetlhtgaifalrrdqvrmpgggivtrevvehfgavaivamddngnipmvyqyr
htygrrlwelpaglldvagepphltaarelreevglqastwqvlvdldtapgfsdesvrv
ylatglrevgreqadmtmgwypiaeaarrvlrgeivnsiaiagvlavhavttgfaqprpl
dtewidrptafaarraer

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5i8uB (B:)
maehdfetissetlhtgaifalrrdqvrmpgggivtrevvehfgavaivamddngnipmv
yqyrhtygrrlwelpaglldvagepphltaarelreevglqastwqvlvdldtapgfsde
svrvylatglrevgrpeahheqadmtmgwypiaeaarrvlrgeivnsiaiagvlavhavt
tgfaqprpldtewidrptafaarraer

    Sequence, based on observed residues (ATOM records): (download) 
    >5i8uB (B:)
fetissetlhtgaifalrrdqvrmpgggivtrevvehfgavaivamddngnipmvyqyrh
tygrrlwelpaglldvagepphltaarelreevglqastwqvlvdldtapgfsdesvrvy
latglrevgrpeahheqadmtmgwypiaeaarrvlrgeivnsiaiagvlavhavttgfaq
prpldtewidrptafaarraer

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5i8uC (C:)
maehdfetissetlhtgaifalrrdqvrmpgggivtrevvehfgavaivamddngnipmv
yqyrhtygrrlwelpaglldvagepphltaarelreevglqastwqvlvdldtapgfsde
svrvylatglrevgrpeahheqadmtmgwypiaeaarrvlrgeivnsiaiagvlavhavt
tgfaqprpldtewidrptafaarraer

    Sequence, based on observed residues (ATOM records): (download) 
    >5i8uC (C:)
dfetissetlhtgaifalrrdqvrmpgggivtrevvehfgavaivamddngnipmvyqyr
htygrrlwelpaglldvagepphltaarelreevglqastwqvlvdldtapgfsdesvrv
ylatglrevgrpeahheqadmtmgwypiaeaarrvlrgeivnsiaiagvlavhavttgfa
qprpldtewidrptafaarraer

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5i8uD (D:)
maehdfetissetlhtgaifalrrdqvrmpgggivtrevvehfgavaivamddngnipmv
yqyrhtygrrlwelpaglldvagepphltaarelreevglqastwqvlvdldtapgfsde
svrvylatglrevgrpeahheqadmtmgwypiaeaarrvlrgeivnsiaiagvlavhavt
tgfaqprpldtewidrptafaarraer

    Sequence, based on observed residues (ATOM records): (download) 
    >5i8uD (D:)
dfetissetlhtgaifalrrdqvrmpgggivtrevvehfgavaivamddngnipmvyqyr
htygrrlwelpaglldvagepphltaarelreevglqastwqvlvdldtapgfsdesvrv
ylatglrevmtmgwypiaeaarrvlrgeivnsiaiagvlavhavttgfaqprpldtewid
rptafaarraer

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5i8uE (E:)
maehdfetissetlhtgaifalrrdqvrmpgggivtrevvehfgavaivamddngnipmv
yqyrhtygrrlwelpaglldvagepphltaarelreevglqastwqvlvdldtapgfsde
svrvylatglrevgrpeahheqadmtmgwypiaeaarrvlrgeivnsiaiagvlavhavt
tgfaqprpldtewidrptafaarraer

    Sequence, based on observed residues (ATOM records): (download) 
    >5i8uE (E:)
fetissetlhtgaifalrrdqvrmpgggivtrevvehfgavaivamddngnipmvyqyrh
tygrrlwelpaglldvagepphltaarelreevglqastwqvlvdldtapgfsdesvrvy
latglrevmtmgwypiaeaarrvlrgeivnsiaiagvlavhavttgfaqprpldtewidr
ptafaarrae

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >5i8uF (F:)
maehdfetissetlhtgaifalrrdqvrmpgggivtrevvehfgavaivamddngnipmv
yqyrhtygrrlwelpaglldvagepphltaarelreevglqastwqvlvdldtapgfsde
svrvylatglrevgrpeahheqadmtmgwypiaeaarrvlrgeivnsiaiagvlavhavt
tgfaqprpldtewidrptafaarraer

    Sequence, based on observed residues (ATOM records): (download) 
    >5i8uF (F:)
fetissetlhtgaifalrrdqvrmpgggivtrevvehfgavaivamddngnipmvyqyrh
tygrrlwelpaglldvagepphltaarelreevglqastwqvlvdldtapgfsdesvrvy
latglrevgrpqadmtmgwypiaeaarrvlrgeivnsiaiagvlavhavttgfaqprpld
tewidrptafaarrae

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >5i8uG (G:)
maehdfetissetlhtgaifalrrdqvrmpgggivtrevvehfgavaivamddngnipmv
yqyrhtygrrlwelpaglldvagepphltaarelreevglqastwqvlvdldtapgfsde
svrvylatglrevgrpeahheqadmtmgwypiaeaarrvlrgeivnsiaiagvlavhavt
tgfaqprpldtewidrptafaarraer

    Sequence, based on observed residues (ATOM records): (download) 
    >5i8uG (G:)
dfetissetlhtgaifalrrdqvrmpgggivtrevvehfgavaivamddngnipmvyqyr
htygrrlwelpaglldvagepphltaarelreevglqastwqvlvdldtapgfsdesvrv
ylatglrevgrpqadmtmgwypiaeaarrvlrgeivnsiaiagvlavhavttgfaqprpl
dtewidrptafaarrae