PDB entry 5hw2

View 5hw2 on RCSB PDB site
Description: Crystal Structure of Adenylosuccinate Lyase from Francisella tularensis Complexed with fumaric acid
Class: lyase
Keywords: Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID, Lyase
Deposited on 2016-01-28, released 2016-02-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-02-10, with a file datestamp of 2016-02-05.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: adenylosuccinate lyase
    Species: Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4) [TaxId:177416]
    Gene: purB, FTT_0015, BZ14_879
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5NIQ1 (0-431)
      • expression tag (432-437)
    Domains in SCOPe 2.08: d5hw2a1, d5hw2a2
  • Chain 'B':
    Compound: adenylosuccinate lyase
    Species: Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4) [TaxId:177416]
    Gene: purB, FTT_0015, BZ14_879
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5NIQ1 (0-431)
      • expression tag (432)
    Domains in SCOPe 2.08: d5hw2b1, d5hw2b2
  • Chain 'C':
    Compound: adenylosuccinate lyase
    Species: Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4) [TaxId:177416]
    Gene: purB, FTT_0015, BZ14_879
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5hw2c_
  • Chain 'D':
    Compound: adenylosuccinate lyase
    Species: Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4) [TaxId:177416]
    Gene: purB, FTT_0015, BZ14_879
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5hw2d_
  • Heterogens: K, FUM, PO4, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5hw2A (A:)
mikrydvaeiskiwadenkyakmlevelailealedrmvpkgtaaeiraraqirpervde
iekvtkhdiiafctsiaeqftaetgkffhfgvtssdiidsalslqirdsmsyvikdleal
cdslltkaeetkeiitmgrshgmfaepmsfgqkflgayvefkrrlkdlkdfqkdgltvqf
sgavgnycilttedekkaadilglpveevstqviprdriaklisihgliasaierlavei
rhlhrsdvfevyegfskgqkgsstmphkknpistenltgmarmlrshvsialencvlwhe
rdishssaerfylpdnfgimvyalrrmkntidnlvvqrdiiedrvrstsaylssfylhfl
vantpfmredcykivqqvafdlkqgesfskklqkvmhdehniildipemdfegikktylk
eidhvfdrsvkargenly

    Sequence, based on observed residues (ATOM records): (download) 
    >5hw2A (A:)
mikrydvaeiskiwadenkyakmlevelailealedrmvpkgtaaeiraraqirpervde
iekvtkhdiiafctsiaeqftaetgkffhfgvtssdiidsalslqirdsmsyvikdleal
cdslltkaeetkeiitmgrshgmfaepmsfgqkflgayvefkrrlkdlkdfqkdgltvqf
sgavgnycilttedekkaadilglpveevstqviprdriaklisihgliasaierlavei
rhlhrsdvfevyegfkknpistenltgmarmlrshvsialencvlwherdishssaerfy
lpdnfgimvyalrrmkntidnlvvqrdiiedrvrstsaylssfylhflvantpfmredcy
kivqqvesfskklqkvmhdehniildipemdfegikktylkeidhvfdrsvkargenly

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5hw2B (B:)
mikrydvaeiskiwadenkyakmlevelailealedrmvpkgtaaeiraraqirpervde
iekvtkhdiiafctsiaeqftaetgkffhfgvtssdiidsalslqirdsmsyvikdleal
cdslltkaeetkeiitmgrshgmfaepmsfgqkflgayvefkrrlkdlkdfqkdgltvqf
sgavgnycilttedekkaadilglpveevstqviprdriaklisihgliasaierlavei
rhlhrsdvfevyegfskgqkgsstmphkknpistenltgmarmlrshvsialencvlwhe
rdishssaerfylpdnfgimvyalrrmkntidnlvvqrdiiedrvrstsaylssfylhfl
vantpfmredcykivqqvafdlkqgesfskklqkvmhdehniildipemdfegikktylk
eidhvfdrsvkargenly

    Sequence, based on observed residues (ATOM records): (download) 
    >5hw2B (B:)
mikrydvaeiskiwadenkyakmlevelailealedrmvpkgtaaeiraraqirpervde
iekvtkhdiiafctsiaeqftaetgkffhfgvtssdiidsalslqirdsmsyvikdleal
cdslltkaeetkeiitmgrshgmfaepmsfgqkflgayvefkrrlkdlkdfqkdgltvqf
sgavgnycilttedekkaadilglpveevstqviprdriaklisihgliasaierlavei
rhlhrsdvfevyegfphkknpistenltgmarmlrshvsialencvlwherdishssaer
fylpdnfgimvyalrrmkntidnlvvqrdiiedrvrstsaylssfylhflvantpfmred
cykivqqvesfskklqkvmhdehniildipemdfegikktylkeidhvfdrsvkar

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5hw2C (C:)
mikrydvaeiskiwadenkyakmlevelailealedrmvpkgtaaeiraraqirpervde
iekvtkhdiiafctsiaeqftaetgkffhfgvtssdiidsalslqirdsmsyvikdleal
cdslltkaeetkeiitmgrshgmfaepmsfgqkflgayvefkrrlkdlkdfqkdgltvqf
sgavgnycilttedekkaadilglpveevstqviprdriaklisihgliasaierlavei
rhlhrsdvfevyegfskgqkgsstmphkknpistenltgmarmlrshvsialencvlwhe
rdishssaerfylpdnfgimvyalrrmkntidnlvvqrdiiedrvrstsaylssfylhfl
vantpfmredcykivqqvafdlkqgesfskklqkvmhdehniildipemdfegikktylk
eidhvfdrsvkargenly

    Sequence, based on observed residues (ATOM records): (download) 
    >5hw2C (C:)
mikrydvaeiskiwadenkyakmlevelailealedrvpkgtaaeiraraqirpervdei
ekvtkhdiiafctsiaeqftaetgkffhfgvtssdiidsalslqirdsmsyvikdlealc
dslltkaeetkeiitmgrshgmfaepmsfgqkflgayvefkrrlkdlkdfqkdgltvqfs
gavgnycilttedekkaadilglpveevstqviprdriaklisihgliasaierlaveir
hlhrsdvfevyegfgqkgsstmphkknpistenltgmarmlrshvsialencvlwherdi
shssaerfylpdnfgimvyalrrmkntidnlvvqrdiiedrvrstsaylssfylhflvan
tpfmredcykivqqvgesfskklqkvmhdehniildipemdfegikktylkeidhvfdrs
vk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5hw2D (D:)
mikrydvaeiskiwadenkyakmlevelailealedrmvpkgtaaeiraraqirpervde
iekvtkhdiiafctsiaeqftaetgkffhfgvtssdiidsalslqirdsmsyvikdleal
cdslltkaeetkeiitmgrshgmfaepmsfgqkflgayvefkrrlkdlkdfqkdgltvqf
sgavgnycilttedekkaadilglpveevstqviprdriaklisihgliasaierlavei
rhlhrsdvfevyegfskgqkgsstmphkknpistenltgmarmlrshvsialencvlwhe
rdishssaerfylpdnfgimvyalrrmkntidnlvvqrdiiedrvrstsaylssfylhfl
vantpfmredcykivqqvafdlkqgesfskklqkvmhdehniildipemdfegikktylk
eidhvfdrsvkargenly

    Sequence, based on observed residues (ATOM records): (download) 
    >5hw2D (D:)
mikrydvaeiskiwadenkyakmlevelailealedrmvpkgtaaeiraraqirpervde
iekvtkhdiiafctsiaeqftaetgkffhfgvtssdiidsalslqirdsmsyvikdleal
cdslltkaeetkeiitmgrshgmfaepmsfgqkflgayvefkrrlkdlkdfqkdgltvqf
sgavgnycilttedekkaadilglpveevstqviprdriaklisihgliasaierlavei
rhlhrsdvfevyegfskgphkknpistenltgmarmlrshvsialencvlwherdishss
aerfylpdnfgimvyalrrmkntidnlvvqrdiiedrvrstsaylssfylhflvantpfm
redcykivqqvesfskklqkvmhdehniildipemdfegikktylkeidhvfdrsvk