PDB entry 5hvo

View 5hvo on RCSB PDB site
Description: Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A
Class: transferase
Keywords: trehalose-6-phosphate synthase, TRANSFERASE
Deposited on 2016-01-28, released 2017-05-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-11, with a file datestamp of 2019-12-06.
Experiment type: XRAY
Resolution: 2.47 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Alpha,alpha-trehalose-phosphate synthase (UDP-forming)
    Species: Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) [TaxId:330879]
    Gene: AFUA_2G04010
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5hvoa_
  • Chain 'B':
    Compound: Alpha,alpha-trehalose-phosphate synthase (UDP-forming)
    Species: Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) [TaxId:330879]
    Gene: AFUA_2G04010
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5hvob_
  • Chain 'C':
    Compound: Alpha,alpha-trehalose-phosphate synthase (UDP-forming)
    Species: Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) [TaxId:330879]
    Gene: AFUA_2G04010
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5hvoc_
  • Chain 'D':
    Compound: Alpha,alpha-trehalose-phosphate synthase (UDP-forming)
    Species: Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) [TaxId:330879]
    Gene: AFUA_2G04010
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5hvod_
  • Heterogens: UDP, VDM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5hvoA (A:)
msstngsegdhrllivsnrlpitirrseggkyefsmssgglvtglsglsktttfqwygwp
glevpedelgsvkkrlkdefnatpvfmddkladrhyngfsnsilwpllhyhpgeivfdeg
awdayreanllfaktivkeaqdgdliwvqdyhlmllpellraelraagkkankigfflht
pfpsseiyrilpvrgqllrgvlhcdligfhtydyarhflsscshllglvttpssvkyegr
svavgafpigidpdkftdglkspkvqnriaslenkfqgtklmvsvdrldyikgipqklha
levflqnhpewvgkvvlvqvavpsrqdveeyqnlravvnelvgringkfgtvdympihfm
hksvsfdelialyaasdacvvsstrdgmnlvsfeyiatqqkrkgvlilsefagaaqslng
slvvnpwnteelarayheavsmsdeqrarkfeklykyiskytsafwgksfvaellqcss

    Sequence, based on observed residues (ATOM records): (download) 
    >5hvoA (A:)
rllivsnrlpitirrsekyefsmsglsglsktttfqwygwpglevpedelgsvkkrlkde
fnatpvfmddkladrhyngfsnsilwpllhyhpgeivfdegawdayreanllfaktivke
aqdgdliwvqdyhlmllpellraelraagkkankigfflhtpfpsseiyrilpvrgqllr
gvlhcdligfhtydyarhflsscshllglvttpssvkyegrsvavgafpigidpdkftdg
lkspkvqnriaslenkfqgtklmvsvdrldyikgipqklhalevflqnhpewvgkvvlvq
vavpsrqdveeyqnlravvnelvgringkfgtvdympihfmhksvsfdelialyaasdac
vvsstrdgmnlvsfeyiatqqkrkgvlilsefagaaqslngslvvnpwnteelarayhea
vsmsdeqrarkfeklykyiskytsafwgksfvaellqcs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5hvoB (B:)
msstngsegdhrllivsnrlpitirrseggkyefsmssgglvtglsglsktttfqwygwp
glevpedelgsvkkrlkdefnatpvfmddkladrhyngfsnsilwpllhyhpgeivfdeg
awdayreanllfaktivkeaqdgdliwvqdyhlmllpellraelraagkkankigfflht
pfpsseiyrilpvrgqllrgvlhcdligfhtydyarhflsscshllglvttpssvkyegr
svavgafpigidpdkftdglkspkvqnriaslenkfqgtklmvsvdrldyikgipqklha
levflqnhpewvgkvvlvqvavpsrqdveeyqnlravvnelvgringkfgtvdympihfm
hksvsfdelialyaasdacvvsstrdgmnlvsfeyiatqqkrkgvlilsefagaaqslng
slvvnpwnteelarayheavsmsdeqrarkfeklykyiskytsafwgksfvaellqcss

    Sequence, based on observed residues (ATOM records): (download) 
    >5hvoB (B:)
rllivsnrlpitiryefsmsglsglsktttfqwygwpglevpedelgsvkkrlkdefnat
pvfmddkladrhyngfsnsilwpllhyhpgeivfdegawdayreanllfaktivkeaqdg
dliwvqdyhlmllpellraelraagkkankigfflhtpfpsseiyrilpvrgqllrgvlh
cdligfhtydyarhflsscshllglvttpssvkyegrsvavgafpigidpdkftdglksp
kvqnriaslenkfqgtklmvsvdrldyikgipqklhalevflqnhpewvgkvvlvqvavp
srqdveeyqnlravvnelvgringkfgtvdympihfmhksvsfdelialyaasdacvvss
trdgmnlvsfeyiatqqkrkgvlilsefagaaqslngslvvnpwnteelarayheavsms
deqrarkfeklykyiskytsafwgksfvaellqc

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5hvoC (C:)
msstngsegdhrllivsnrlpitirrseggkyefsmssgglvtglsglsktttfqwygwp
glevpedelgsvkkrlkdefnatpvfmddkladrhyngfsnsilwpllhyhpgeivfdeg
awdayreanllfaktivkeaqdgdliwvqdyhlmllpellraelraagkkankigfflht
pfpsseiyrilpvrgqllrgvlhcdligfhtydyarhflsscshllglvttpssvkyegr
svavgafpigidpdkftdglkspkvqnriaslenkfqgtklmvsvdrldyikgipqklha
levflqnhpewvgkvvlvqvavpsrqdveeyqnlravvnelvgringkfgtvdympihfm
hksvsfdelialyaasdacvvsstrdgmnlvsfeyiatqqkrkgvlilsefagaaqslng
slvvnpwnteelarayheavsmsdeqrarkfeklykyiskytsafwgksfvaellqcss

    Sequence, based on observed residues (ATOM records): (download) 
    >5hvoC (C:)
hrllivsnrlpitiyefsmglsglsktttfqwygwpglevpedelgsvkkrlkdefnatp
vfmddkladrhyngfsnsilwpllhyhpgeivfdegawdayreanllfaktivkeaqdgd
liwvqdyhlmllpellraelraagkkankigfflhtpfpsseiyrilpvrgqllrgvlhc
dligfhtydyarhflsscshllglvttpssvkyegrsvavgafpigidpdkftdglkspk
vqnriaslenkfqgtklmvsvdrldyikgipqklhalevflqnhpewvgkvvlvqvavps
rqdveeyqnlravvnelvgringkfgtvdympihfmhksvsfdelialyaasdacvvsst
rdgmnlvsfeyiatqqkrkgvlilsefagaaqslngslvvnpwnteelarayheavsmsd
eqrarkfeklykyiskytsafwgksfvaellqcs

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5hvoD (D:)
msstngsegdhrllivsnrlpitirrseggkyefsmssgglvtglsglsktttfqwygwp
glevpedelgsvkkrlkdefnatpvfmddkladrhyngfsnsilwpllhyhpgeivfdeg
awdayreanllfaktivkeaqdgdliwvqdyhlmllpellraelraagkkankigfflht
pfpsseiyrilpvrgqllrgvlhcdligfhtydyarhflsscshllglvttpssvkyegr
svavgafpigidpdkftdglkspkvqnriaslenkfqgtklmvsvdrldyikgipqklha
levflqnhpewvgkvvlvqvavpsrqdveeyqnlravvnelvgringkfgtvdympihfm
hksvsfdelialyaasdacvvsstrdgmnlvsfeyiatqqkrkgvlilsefagaaqslng
slvvnpwnteelarayheavsmsdeqrarkfeklykyiskytsafwgksfvaellqcss

    Sequence, based on observed residues (ATOM records): (download) 
    >5hvoD (D:)
hrllivsnrlpitiryefsmsglsglsktttfqwygwpglevpedelgsvkkrlkdefna
tpvfmddkladrhyngfsnsilwpllhyhpgeivfdegawdayreanllfaktivkeaqd
gdliwvqdyhlmllpellraelraagkkankigfflhtpfpsseiyrilpvrgqllrgvl
hcdligfhtydyarhflsscshllglvttpssvkyegrsvavgafpigidpdkftdglks
pkvqnriaslenkfqgtklmvsvdrldyikgipqklhalevflqnhpewvgkvvlvqvav
psrqdveeyqnlravvnelvgringkfgtvdympihfmhksvsfdelialyaasdacvvs
strdgmnlvsfeyiatqqkrkgvlilsefagaaqslngslvvnpwnteelarayheavsm
sdeqrarkfeklykyiskytsafwgksfvaellqcs