PDB entry 5hrx

View 5hrx on RCSB PDB site
Description: Crystal structure of the fifth bromodomain of human PB1 in complex with 1-butylisochromeno[3,4-c]pyrazol-5(2H)-one) compound
Class: transcription
Keywords: PBRM1, BRG1-associated factor 180, transcription, chromatin remodeling
Deposited on 2016-01-24, released 2016-10-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-10-26, with a file datestamp of 2016-10-21.
Experiment type: XRAY
Resolution: 1.73 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein polybromo-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PBRM1, BAF180, PB1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5hrxa_
  • Chain 'B':
    Compound: Protein polybromo-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PBRM1, BAF180, PB1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5hrxb_
  • Heterogens: EDO, 64F, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5hrxA (A:)
smsgispkkskymtpmqqklnevyeavknytdkrgrrlsaiflrlpsrselpdyyltikk
pmdmekirshmmankyqdidsmvedfvmmfnnactynepesliykdalvlhkvlletrrd
legd

    Sequence, based on observed residues (ATOM records): (download) 
    >5hrxA (A:)
ymtpmqqklnevyeavknytdkrgrrlsaiflrlpsrselpdyyltikkpmdmekirshm
mankyqdidsmvedfvmmfnnactynepesliykdalvlhkvlletrrdl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5hrxB (B:)
smsgispkkskymtpmqqklnevyeavknytdkrgrrlsaiflrlpsrselpdyyltikk
pmdmekirshmmankyqdidsmvedfvmmfnnactynepesliykdalvlhkvlletrrd
legd

    Sequence, based on observed residues (ATOM records): (download) 
    >5hrxB (B:)
mtpmqqklnevyeavknytdkrgrrlsaiflrlpsrselpdyyltikkpmdmekirshmm
ankyqdidsmvedfvmmfnnactynepesliykdalvlhkvlletrrd