PDB entry 5hbv
View 5hbv on RCSB PDB site
Description: Complex structure of Fab35 and mouse nAChR alpha1
Class: transport protein/toxin
Keywords: Nicotinic acetylcholine receptor alpha1, Fab35, Complex, Myasthenia gravis, TRANSPORT PROTEIN-TOXIN complex
Deposited on
2016-01-02, released
2017-05-03
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-07-29, with a file datestamp of
2020-07-04.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.24
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: alpha-bungarotoxin isoform v31
Species: Bungarus multicinctus [TaxId:8616]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5hbva_ - Chain 'B':
Compound: Acetylcholine receptor subunit alpha 1
Species: Mus musculus [TaxId:10090]
Gene: Chrna1, Acra
Database cross-references and differences (RAF-indexed):
- Uniprot P04756 (2-211)
- expression tag (0-1)
- engineered mutation (8)
- engineered mutation (149)
- engineered mutation (155)
Domains in SCOPe 2.08: d5hbvb1, d5hbvb2 - Chain 'C':
Compound: Fab35, Light Chain
Species: Rattus norvegicus [TaxId:10116]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5hbvc1, d5hbvc2 - Chain 'D':
Compound: Fab35, Heavy Chain
Species: Rattus norvegicus [TaxId:10116]
Database cross-references and differences (RAF-indexed):
- Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>5hbvA (A:)
ivchttatspisavtcppgenlcyrkmwcdvfcssrgkvvelgcaatcpskkpyeevtcc
stdkcnphpkqrpg
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>5hbvB (B:)
ksehetrleaklfedyssvvrpvedhreivqvtvglqliqlinvdevnqivttnvrlkqq
wvdynlkwnpddyggvkkihipsekiwrpdvvlynnadgdfaivkftkvlldytghitwt
ppaifksyceiivthfpfdeqncsmklgtrtydgsavainpesdqpdlsnfmesgewvik
eargwkhwvfysccpttpyldityhfvmqrlp
- Chain 'C':
Sequence, based on SEQRES records: (download)
>5hbvC (C:)
divitqspsllsasvgdrvtltckgsqnidnylawyqqklgeapklliyktnslqtgips
rfsgsgsgtdytltisslhsedlatyycyqyingytfgtgtklelkradaaptvsifpps
teqlatggasvvclmnnfyprdisvkwkidgterrdgvldsvtdqdskdstysmsstlsl
tkadyeshnlytcevvhktssspvvksfnrnec
Sequence, based on observed residues (ATOM records): (download)
>5hbvC (C:)
divitqspsllsasvgdrvtltckgsqnidnylawyqqklgeapklliyktnslqtgips
rfsgsgsgtdytltisslhsedlatyycyqyingytfgtgtklelkradaaptvsifpps
teqlatggasvvclmnnfyprdisvkwkidgterrdgvldsvtdqdskdstysmsstlsl
tkadyeshnlytcevvhktssspvvksfnrn
- Chain 'D':
No sequence available.