PDB entry 5h0x

View 5h0x on RCSB PDB site
Description: Crystal structure of H88S mutated human transthyretin
Class: transport protein
Keywords: transthhyretin, amyloidosis, transporter, TRANSPORT PROTEIN
Deposited on 2016-10-07, released 2017-06-14
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-06-14, with a file datestamp of 2017-06-09.
Experiment type: XRAY
Resolution: 1.57 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Gene: TTR, PALB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02766 (9-End)
      • expression tag (8)
      • engineered mutation (86)
    Domains in SCOPe 2.06: d5h0xa1, d5h0xa2
  • Chain 'B':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Gene: TTR, PALB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02766 (9-End)
      • expression tag (8)
      • engineered mutation (86)
    Domains in SCOPe 2.06: d5h0xb1, d5h0xb2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5h0xA (A:)
    ahhhhhhmsplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltte
    eefvegiykveidtksywkalgispfsehaevvftandsgprrytiaallspysysttav
    vtnpke
    

    Sequence, based on observed residues (ATOM records): (download)
    >5h0xA (A:)
    splmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
    kveidtksywkalgispfsehaevvftandsgprrytiaallspysysttavvtn
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5h0xB (B:)
    ahhhhhhmsplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltte
    eefvegiykveidtksywkalgispfsehaevvftandsgprrytiaallspysysttav
    vtnpke
    

    Sequence, based on observed residues (ATOM records): (download)
    >5h0xB (B:)
    splmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
    kveidtksywkalgispfsehaevvftandsgprrytiaallspysysttavvtn