PDB entry 5gzo

View 5gzo on RCSB PDB site
Description: Structure of neutralizing antibody bound to Zika envelope protein
Class: viral protein/immune system
Keywords: Zika virus, Human neutralizing antibodies, Envelope protein, Molecular determinants, VIRAL PROTEIN-IMMUNE SYSTEM complex
Deposited on 2016-09-29, released 2017-01-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-08-30, with a file datestamp of 2017-08-25.
Experiment type: XRAY
Resolution: 2.76 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Genome polyprotein
    Species: Zika virus [TaxId:64320]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5gzoa1, d5gzoa2
  • Chain 'B':
    Compound: Genome polyprotein
    Species: Zika virus [TaxId:64320]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5gzob1, d5gzob2
  • Chain 'C':
    Compound: antibody heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5GZO (0-End)
  • Chain 'D':
    Compound: Antibody Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5GZO (0-End)
    Domains in SCOPe 2.07: d5gzod1, d5gzod2
  • Chain 'H':
    Compound: antibody heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5GZO (0-End)
  • Chain 'L':
    Compound: Antibody Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5GZO (0-End)
    Domains in SCOPe 2.07: d5gzol1, d5gzol2

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5gzoA (A:)
    ircigvsnrdfvegmsggtwvdvvlehggcvtvmaqdkptvdielvtttvsnmaevrsyc
    yeasisdmasdsrcptqgeayldkqsdtqyvckrtlvdrgwgngcglfgkgslvtcakfa
    cskkmtgksiqpenleyrimlsvhgsqhsgmivndtghetdenrakveitpnspraeatl
    ggfgslgldceprtgldfsdlyyltmnnkhwlvhkewfhdiplpwhagadtgtphwnnke
    alvefkdahakrqtvvvlgsqegavhtalagaleaemdgakgrlssghlkcrlkmdklrl
    kgvsyslctaaftftkipaetlhgtvtvevqyagtdgpckvpaqmavdmqtltpvgrlit
    anpvitestenskmmleldppfgdsyivigvgekkithhwhrsgstigk
    

    Sequence, based on observed residues (ATOM records): (download)
    >5gzoA (A:)
    ircigvsnrdfvegmsggtwvdvvlehggcvtvmaqdkptvdielvtttvsnmaevrsyc
    yeasisdmasdsrcptqgeayldkqsdtqyvckrtlvdrgwgngcglfgkgslvtcakfa
    cskkmtgksiqpenleyrimlsvhgsenrakveitpnspraeatlggfgslgldceprtg
    ldfsdlyyltmnnkhwlvhkewfhdiplpwhagadtgtphwnnkealvefkdahakrqtv
    vvlgsqegavhtalagaleaemdgakgrlssghlkcrlkmdklrlkgvsyslctaaftft
    kipaetlhgtvtvevqyagtdgpckvpaqmavdmqtltpvgrlitanpvitestenskmm
    leldppfgdsyivigvgekkithhwhrsgs
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5gzoB (B:)
    ircigvsnrdfvegmsggtwvdvvlehggcvtvmaqdkptvdielvtttvsnmaevrsyc
    yeasisdmasdsrcptqgeayldkqsdtqyvckrtlvdrgwgngcglfgkgslvtcakfa
    cskkmtgksiqpenleyrimlsvhgsqhsgmivndtghetdenrakveitpnspraeatl
    ggfgslgldceprtgldfsdlyyltmnnkhwlvhkewfhdiplpwhagadtgtphwnnke
    alvefkdahakrqtvvvlgsqegavhtalagaleaemdgakgrlssghlkcrlkmdklrl
    kgvsyslctaaftftkipaetlhgtvtvevqyagtdgpckvpaqmavdmqtltpvgrlit
    anpvitestenskmmleldppfgdsyivigvgekkithhwhrsgstigk
    

    Sequence, based on observed residues (ATOM records): (download)
    >5gzoB (B:)
    ircigvsnrdfvegmsggtwvdvvlehggcvtvmaqdkptvdielvtttvsnmaevrsyc
    yeasisdmasdsrcptqgeayldkqsdtqyvckrtlvdrgwgngcglfgkgslvtcakfa
    cskkmtgksiqpenleyrimlsvhgsenrakveitpnspraeatlggfgslgldceprtg
    ldfsdlyyltmnnkhwlvhkewfhdiplpwhagadtgtphwnnkealvefkdahakrqtv
    vvlgsqegavhtalagaleaemdgakgrlssghlkcrlkmdklrlkgvsyslctaaftft
    kipaetlhgtvtvevqyagtdgpckvpaqmavdmqtltpvgrlitanpvitestenskmm
    leldppfgdsyivigvgekkithhwhrsgs
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >5gzoD (D:)
    divmtqspsslsasvgdrvtitcrasqgirndlgwyqqkpgkapkrliyaasslqsgvps
    rfsgsgsgteftltisslqpedfatyyclqhnsyprtfgqgtkveikrtvaapsvfifpp
    sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
    lskadyekhkvyacevthqglsspvtksfnrgecs
    

    Sequence, based on observed residues (ATOM records): (download)
    >5gzoD (D:)
    divmtqspsslsasvgdrvtitcrasqgirndlgwyqqkpgkapkrliyaasslqsgvps
    rfsgsgsgteftltisslqpedfatyyclqhnsyprtfgqgtkveikrtvaapsvfifpp
    sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
    lskadyekhkvyacevthqglsspvtksfnrge
    

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >5gzoL (L:)
    divmtqspsslsasvgdrvtitcrasqgirndlgwyqqkpgkapkrliyaasslqsgvps
    rfsgsgsgteftltisslqpedfatyyclqhnsyprtfgqgtkveikrtvaapsvfifpp
    sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
    lskadyekhkvyacevthqglsspvtksfnrgecs
    

    Sequence, based on observed residues (ATOM records): (download)
    >5gzoL (L:)
    divmtqspsslsasvgdrvtitcrasqgirndlgwyqqkpgkapkrliyaasslqsgvps
    rfsgsgsgteftltisslqpedfatyyclqhnsyprtfgqgtkveikrtvaapsvfifpp
    sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
    lskadyekhkvyacevthqglsspvtksfnrge