PDB entry 5fwr

View 5fwr on RCSB PDB site
Description: Breaking down the wall: mutation of the tyrosine gate of the universal Escherichia coli fimbrial adhesin FimH
Class: cell adhesion
Keywords: cell adhesion, bacterial adhesin, type 1 fimbriae, urinary tract infection, variable immunoglobulin fold
Deposited on 2016-02-21, released 2016-11-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-09-25, with a file datestamp of 2019-09-20.
Experiment type: XRAY
Resolution: 2.13 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: FimH
    Species: Escherichia coli [TaxId:562]
    Gene: fimH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5fwra_
  • Chain 'B':
    Compound: FimH
    Species: Escherichia coli [TaxId:562]
    Gene: fimH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5fwrb_
  • Chain 'C':
    Compound: FimH
    Species: Escherichia coli [TaxId:562]
    Gene: fimH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5fwrc_
  • Chain 'D':
    Compound: FimH
    Species: Escherichia coli [TaxId:562]
    Gene: fimH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5fwrd_
  • Chain 'E':
    Compound: FimH
    Species: Escherichia coli [TaxId:562]
    Gene: fimH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5fwre_
  • Chain 'F':
    Compound: FimH
    Species: Escherichia coli [TaxId:562]
    Gene: fimH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5fwrf_
  • Chain 'G':
    Compound: FimH
    Species: Escherichia coli [TaxId:562]
    Gene: fimH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5fwrg_
  • Chain 'H':
    Compound: FimH
    Species: Escherichia coli [TaxId:562]
    Gene: fimH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5fwrh_
  • Heterogens: 3X8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5fwrA (A:)
facktangtaipigggsanvyvnlapvvnvgqnlvvdlstqifchndypetitdyvtlqr
gsayggvlsnfsgtvkysgssypfpttsetprvvynsrtdkpwpvalyltpvssaggvai
kagsliavlilrqtnnynsddfqfvwniyanndvvvpt

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5fwrB (B:)
facktangtaipigggsanvyvnlapvvnvgqnlvvdlstqifchndypetitdyvtlqr
gsayggvlsnfsgtvkysgssypfpttsetprvvynsrtdkpwpvalyltpvssaggvai
kagsliavlilrqtnnynsddfqfvwniyanndvvvpt

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5fwrC (C:)
facktangtaipigggsanvyvnlapvvnvgqnlvvdlstqifchndypetitdyvtlqr
gsayggvlsnfsgtvkysgssypfpttsetprvvynsrtdkpwpvalyltpvssaggvai
kagsliavlilrqtnnynsddfqfvwniyanndvvvpt

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5fwrD (D:)
facktangtaipigggsanvyvnlapvvnvgqnlvvdlstqifchndypetitdyvtlqr
gsayggvlsnfsgtvkysgssypfpttsetprvvynsrtdkpwpvalyltpvssaggvai
kagsliavlilrqtnnynsddfqfvwniyanndvvvpt

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5fwrE (E:)
facktangtaipigggsanvyvnlapvvnvgqnlvvdlstqifchndypetitdyvtlqr
gsayggvlsnfsgtvkysgssypfpttsetprvvynsrtdkpwpvalyltpvssaggvai
kagsliavlilrqtnnynsddfqfvwniyanndvvvpt

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5fwrF (F:)
facktangtaipigggsanvyvnlapvvnvgqnlvvdlstqifchndypetitdyvtlqr
gsayggvlsnfsgtvkysgssypfpttsetprvvynsrtdkpwpvalyltpvssaggvai
kagsliavlilrqtnnynsddfqfvwniyanndvvvpt

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5fwrG (G:)
facktangtaipigggsanvyvnlapvvnvgqnlvvdlstqifchndypetitdyvtlqr
gsayggvlsnfsgtvkysgssypfpttsetprvvynsrtdkpwpvalyltpvssaggvai
kagsliavlilrqtnnynsddfqfvwniyanndvvvpt

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5fwrH (H:)
facktangtaipigggsanvyvnlapvvnvgqnlvvdlstqifchndypetitdyvtlqr
gsayggvlsnfsgtvkysgssypfpttsetprvvynsrtdkpwpvalyltpvssaggvai
kagsliavlilrqtnnynsddfqfvwniyanndvvvpt