PDB entry 5fux

View 5fux on RCSB PDB site
Description: catalytic domain of Thymidine kinase from Trypanosoma brucei with dTMP
Class: transferase
Keywords: transferase, transefrase, thymidine kinase, t.brucei, tbtk, tkii, dtmp
Deposited on 2016-01-31, released 2016-07-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-11-09, with a file datestamp of 2016-11-04.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thymdine kinase
    Species: TRYPANOSOMA BRUCEI [TaxId:5691]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q38CF2 (0-181)
      • engineered mutation (89)
    Domains in SCOPe 2.08: d5fuxa1, d5fuxa2
  • Chain 'B':
    Compound: thymdine kinase
    Species: TRYPANOSOMA BRUCEI [TaxId:5691]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q38CF2 (Start-181)
      • engineered mutation (89)
    Domains in SCOPe 2.08: d5fuxb1, d5fuxb2
  • Heterogens: MG, ZN, PO4, QBT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5fuxA (A:)
ahgrieliigpmfagkttelmrrvqrhkhaqrscyiikytgdtrysegaitshdqralta
nvsvsnlhdvgdewrkydviavdegqffpdvaafcskaadsgkvvivsaldadylqepfe
eicllvsradsvvklsavcmechnrkasftyrtvksderklvggsdmymsvcrscyetkr
nm

    Sequence, based on observed residues (ATOM records): (download) 
    >5fuxA (A:)
ahgrieliigpmfagkttelmrrvqrhkhaqrscyiikytgdtltanvsvsnlhdvgdew
rkydviavdegqffpdvaafcskaadsgkvvivsaldadylqepfeeicllvsradsvvk
lsavcmechnrkasftyrtvksderklvggsdmymsvcrscyetkrnm

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5fuxB (B:)
ahgrieliigpmfagkttelmrrvqrhkhaqrscyiikytgdtrysegaitshdqralta
nvsvsnlhdvgdewrkydviavdegqffpdvaafcskaadsgkvvivsaldadylqepfe
eicllvsradsvvklsavcmechnrkasftyrtvksderklvggsdmymsvcrscyetkr
nm

    Sequence, based on observed residues (ATOM records): (download) 
    >5fuxB (B:)
hgrieliigpmfagkttelmrrvqrhkhaqrscyiikytgltanvsvsnlhdvgdewrky
dviavdegqffpdvaafcskaadsgkvvivsaldadylqepfeeicllvsradsvvklsa
vcmechnrkasftyrtvksderklvggsdmymsvcrscyetkrnm