PDB entry 5fpo

View 5fpo on RCSB PDB site
Description: Structure of Bacterial DNA Ligase with small-molecule ligand 1H- indazol-7-amine (AT4213) in an alternate binding site.
Class: ligase
Keywords: ligase, antibiotic design, protein-ligand complex, fragment screening, alternate binding site, at4213.
Deposited on 2015-12-02, released 2015-12-23
The last revision prior to the SCOPe 2.06 freeze date was dated 2016-01-13, with a file datestamp of 2016-01-08.
Experiment type: XRAY
Resolution: 1.83 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA ligase
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5fpoa_
  • Heterogens: 10L, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5fpoA (A:)
madlssrvnelhdllnqysyeyyvednpsvpdseydkllhelikieeehpeyktvdsptv
rvggeaqasfnkvnhdtpmlslgnafneddlrkfdqrireqignveymcelkidglavsl
kyvdgyfvqgltrgdgttgeditenlktihaiplkmkeplnvevrgeaymprrsflrlne
ekekndeqlfanprnaaagslrqldskltakrklsvfiysvndftdfnarsqsealdeld
klgfttnknrarvnnidgvleyiekwtsqreslpydidgivikvndldqqdemgftqksp
rwaiaykfpaeehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5fpoA (A:)
dlssrvnelhdllnqysyeyyvednpsvpdseydkllhelikieeehpeyktvdsptvrv
ggeaqasfnkvnhdtpmlslgnafneddlrkfdqrireqignveymcelkidglavslky
vdgyfvqgltrgdgttgeditenlktihaiplkmkeplnvevrgeaymprrsflrlneek
ekneqlfanprnaaagslrqldskltakrklsvfiysvndftdfnarsqsealdeldklg
fttnknrarvnnidgvleyiekwtsqreslpydidgivikvndldqqdemgftqksprwa
iaykfp