PDB entry 5fdz

View 5fdz on RCSB PDB site
Description: Crystal structure of human PCAF bromodomain in complex with compound BDOMB00091a (compound 14)
Class: signaling protein
Keywords: SIGNALING PROTEIN, bromodomain, Histone acetyltransferase KAT2B, histone, acetylation, acetyllysine, epigenetics, structural genomics consortium (SGC)
Deposited on 2015-12-16, released 2016-01-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-21, with a file datestamp of 2021-07-16.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone acetyltransferase KAT2B
    Species: Homo sapiens [TaxId:9606]
    Gene: KAT2B, PCAF
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q92831 (2-118)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d5fdza_
  • Chain 'B':
    Compound: Histone acetyltransferase KAT2B
    Species: Homo sapiens [TaxId:9606]
    Gene: KAT2B, PCAF
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q92831 (2-118)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d5fdzb_
  • Heterogens: 5X0, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5fdzA (A:)
smgkekskeprdpdqlystlksilqqvkshqsawpfmepvkrteapgyyevirfpmdlkt
mserlknryyvskklfmadlqrvftnckeynppeseyykcanilekfffskikeaglid

    Sequence, based on observed residues (ATOM records): (download) 
    >5fdzA (A:)
dpdqlystlksilqqvkshqsawpfmepvkrteapgyyevirfpmdlktmserlknryyv
skklfmadlqrvftnckeynppeseyykcanilekfffskikeagli

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5fdzB (B:)
smgkekskeprdpdqlystlksilqqvkshqsawpfmepvkrteapgyyevirfpmdlkt
mserlknryyvskklfmadlqrvftnckeynppeseyykcanilekfffskikeaglid

    Sequence, based on observed residues (ATOM records): (download) 
    >5fdzB (B:)
pdqlystlksilqqvkshqsawpfmepvkrteapgyyevirfpmdlktmserlknryyvs
kklfmadlqrvftnckeynppeseyykcanilekfffskikeagli