PDB entry 5f1v

View 5f1v on RCSB PDB site
Description: biomimetic design results in a potent allosteric inhibitor of dihydrodipicolinate synthase from Campylobacter jejuni
Class: LYASE/LYASE inhibitor
Keywords: schiff-base, aldolase, TIM barrel, LYASE-LYASE inhibitor complex
Deposited on 2015-11-30, released 2016-02-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-08, with a file datestamp of 2020-01-03.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 4-hydroxy-tetrahydrodipicolinate synthase
    Species: Campylobacter jejuni [TaxId:197]
    Gene: dapA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5f1va_
  • Chain 'B':
    Compound: 4-hydroxy-tetrahydrodipicolinate synthase
    Species: Campylobacter jejuni [TaxId:197]
    Gene: dapA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5f1vb_
  • Chain 'C':
    Compound: 4-hydroxy-tetrahydrodipicolinate synthase
    Species: Campylobacter jejuni [TaxId:197]
    Gene: dapA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5f1vc_
  • Chain 'D':
    Compound: 4-hydroxy-tetrahydrodipicolinate synthase
    Species: Campylobacter jejuni [TaxId:197]
    Gene: dapA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5f1vd_
  • Heterogens: 3VN, PGE, EDO, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5f1vA (A:)
dkniiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesatltheehrt
cieiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyynkptqqglye
hykaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgnidkcvdllah
eprmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenykeakkindely
ninkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkkykikgf

    Sequence, based on observed residues (ATOM records): (download) 
    >5f1vA (A:)
kniiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesatltheehrtc
ieiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyynkptqqglyeh
ykaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgnidkcvdllahe
prmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenykeakkindelyn
inkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkkykikgf

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5f1vB (B:)
dkniiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesatltheehrt
cieiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyynkptqqglye
hykaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgnidkcvdllah
eprmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenykeakkindely
ninkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkkykikgf

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5f1vC (C:)
dkniiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesatltheehrt
cieiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyynkptqqglye
hykaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgnidkcvdllah
eprmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenykeakkindely
ninkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkkykikgf

    Sequence, based on observed residues (ATOM records): (download) 
    >5f1vC (C:)
kniiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesatltheehrtc
ieiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyynkptqqglyeh
ykaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgnidkcvdllahe
prmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenykeakkindelyn
inkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkkykikgf

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5f1vD (D:)
dkniiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesatltheehrt
cieiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyynkptqqglye
hykaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgnidkcvdllah
eprmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenykeakkindely
ninkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkkykikgf

    Sequence, based on observed residues (ATOM records): (download) 
    >5f1vD (D:)
niiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesatltheehrtci
eiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyynkptqqglyehy
kaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgnidkcvdllahep
rmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenykeakkindelyni
nkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkkykikgf