PDB entry 5f1o

View 5f1o on RCSB PDB site
Description: human CD38 in complex with nanobody MU551
Class: hydrolase/immune system
Keywords: CD38, ADP-ribosyl cyclase, cyclic ADP-ribose, X-crystallography, Calcium signaling, nanobody, MU551, HYDROLASE-IMMUNE SYSTEM complex
Deposited on 2015-11-30, released 2016-06-15
The last revision prior to the SCOPe 2.06 freeze date was dated 2016-06-15, with a file datestamp of 2016-06-10.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CD38
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28907
      • engineered mutation (3)
      • engineered mutation (54)
      • engineered mutation (118)
      • engineered mutation (163)
      • engineered mutation (173)
    Domains in SCOPe 2.06: d5f1oa_
  • Chain 'B':
    Compound: nanobody MU551
    Species: Lama glama [TaxId:9844]
    Gene:
    Database cross-references and differences (RAF-indexed):
    • PDB 5F1O (0-End)
    Domains in SCOPe 2.06: d5f1ob_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5f1oA (A:)
    wrqtwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhpcditeed
    yqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdltwcgefdt
    skinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdkdstfgsv
    evhnlqpekvqtleawvihggredsrdlcqdptikelesiiskrniqfsckniyrpdkfl
    qcvknpedssctsei
    

    Sequence, based on observed residues (ATOM records): (download)
    >5f1oA (A:)
    twsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhpcditeedyqp
    lmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdltwcgefdtski
    nyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdkdstfgsvevh
    nlqpekvqtleawvihgsrdlcqdptikelesiiskrniqfsckniyrpdkflqcvknpe
    c
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5f1oB (B:)
    dvqlqesggglvqaghslrlscvgsgsrfdnyamgwfrqapgkerefvaaiswssgttry
    ldtvkgrftisrdnakstvylqmnslkpedtavyycaaryqpryydsgdmdgyeydnwgq
    gtqvtvssepktpkpqpaaahhhhhhgaaeqkliseedlngaa
    

    Sequence, based on observed residues (ATOM records): (download)
    >5f1oB (B:)
    dvqlqesggglvqaghslrlscvgsgsrfdnyamgwfrqapgkerefvaaiswssgttry
    ldtvkgrftisrdnakstvylqmnslkpedtavyycaaryqpryydsgdmdgyeydnwgq
    gtqvtvss