PDB entry 5enh
View 5enh on RCSB PDB site
Description: Crystal structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in complex with compound-12 N11528 (SGC - Diamond I04-1 fragment screening)
Class: signaling protein
Keywords: bromodomain, PHIP, crystallographic fragment screen, Structural Genomics, Structural Genomics Consortium, SGC, transcription, signaling protein
Deposited on
2015-11-09, released
2016-04-27
The last revision prior to the SCOPe 2.06 freeze date was dated
2016-04-27, with a file datestamp of
2016-04-22.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.33
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: PH-interacting protein
Species: Homo sapiens [TaxId:9606]
Gene: PHIP, WDR11
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d5enha1, d5enha2 - Heterogens: 5QB, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5enhA (A:)
yfqsmsydiqawkkqceellnlifqcedsepfrqpvdlleypdyrdiidtpmdfatvret
leagnyespmelckdvrlifsnskaytpskrsriysmslrlsaffeehissvlsdyksal
rfhkrntitkr
Sequence, based on observed residues (ATOM records): (download)
>5enhA (A:)
smsydiqawkkqceellnlifqcedsepfrqpvdlleypdyrdiidtpmdfatvretlea
gnyespmelckdvrlifsnskaytpskrsriysmslrlsaffeehissvlsdyksalrfh
krn