PDB entry 5ekd

View 5ekd on RCSB PDB site
Description: Human mitochondrial tryptophanyl-tRNA synthetase bound by indolmycin and Mn*ATP.
Class: ligase/antibiotic
Keywords: TrpRS, indolmycin, mitochondrial, complex, LIGASE-ANTIBIOTIC complex
Deposited on 2015-11-03, released 2016-11-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-20, with a file datestamp of 2017-09-15.
Experiment type: XRAY
Resolution: 1.82 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tryptophan--tRNA ligase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: WARS2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5ekda_
  • Chain 'B':
    Compound: Tryptophan--tRNA ligase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: WARS2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5ekdb_
  • Heterogens: 5BX, ATP, MN, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5ekdA (A:)
alhkgsaaapalqkdskkrvfsgiqptgilhlgnylgaieswvrlqdeydsvlysivdlh
sitvpqdpavlrqsildmtavllacginpeksilfqqsqvsehtqlswilscmvrlprlq
hlhqwkakttkqkhdgtvglltypvlqaadillyksthvpvgedqvqhmelvqdlaqgfn
kkygeffpvpesiltsmkkvkslrdpsakmsksdpdklatvritdspeeivqkfrkavtd
ftsevtydpagragvsnivavhaavtglsveevvrrsagmntaryklavadaviekfapi
kreieklkldkdhlekvlqigsakakelaytvcqevkklvgfl

    Sequence, based on observed residues (ATOM records): (download) 
    >5ekdA (A:)
kkrvfsgiqptgilhlgnylgaieswvrlqdeydsvlysivdlhsitvpqdpavlrqsil
dmtavllacginpeksilfqqsqvsehtqlswilscmvrlprlqhlhqwkakttkqkhdg
tvglltypvlqaadillyksthvpvgedqvqhmelvqdlaqgfnkkygeffpvpesilts
mkkvkslrdpsakmsksdpdklatvritdspeeivqkfrkavtdftsevtydpagragvs
nivavhaavtglsveevvrrsagmntaryklavadaviekfapikreieklkldkdhlek
vlqigsakakelaytvcqevkklvgfl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5ekdB (B:)
alhkgsaaapalqkdskkrvfsgiqptgilhlgnylgaieswvrlqdeydsvlysivdlh
sitvpqdpavlrqsildmtavllacginpeksilfqqsqvsehtqlswilscmvrlprlq
hlhqwkakttkqkhdgtvglltypvlqaadillyksthvpvgedqvqhmelvqdlaqgfn
kkygeffpvpesiltsmkkvkslrdpsakmsksdpdklatvritdspeeivqkfrkavtd
ftsevtydpagragvsnivavhaavtglsveevvrrsagmntaryklavadaviekfapi
kreieklkldkdhlekvlqigsakakelaytvcqevkklvgfl

    Sequence, based on observed residues (ATOM records): (download) 
    >5ekdB (B:)
lqkdskkrvfsgiqptgilhlgnylgaieswvrlqdeydsvlysivdlhsitvpqdpavl
rqsildmtavllacginpeksilfqqsqvsehtqlswilscmvrlprlqhlhqwkakttg
tvglltypvlqaadillyksthvpvgedqvqhmelvqdlaqgfnkkygeffpvpesilts
mkkvkslrdpsakmsksdpdklatvritdspeeivqkfrkavtdftsevtydpagragvs
nivavhaavtglsveevvrrsagmntaryklavadaviekfapikreieklkldkdhlek
vlqigsakakelaytvcqevkklvgfl