PDB entry 5eif

View 5eif on RCSB PDB site
Description: dengue 3 ns5 methyltransferase bound to s-adenosyl methionine and fragment nb2c3
Class: transferase
Keywords: transferase, dengue virus, ns5 methyltransferase, fragment-based drug discovery
Deposited on 2015-10-29, released 2016-10-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-09-06, with a file datestamp of 2017-09-01.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Genome polyprotein
    Species: Dengue virus type 3 [TaxId:408870]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27915
      • conflict (49)
    Domains in SCOPe 2.08: d5eifa1, d5eifa2
  • Chain 'C':
    Compound: Genome polyprotein
    Species: Dengue virus type 3 [TaxId:408870]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27915
      • conflict (49)
    Domains in SCOPe 2.08: d5eifc1, d5eifc2
  • Heterogens: SAM, 4M0, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5eifA (A:)
gtgsqgetlgekwkkklnqlsrkefdlykksgitevdrteakeglkrgetthhavsrgsa
klqwfvernmvipegrvidlgcgrggwsyycaglkkvtevrgytkggpgheepvpmstyg
wnivklmsgkdvfylppekcdtllcdigesspsptveesrtirvlkmvepwlknnqfcik
vlnpymptviehlerlqrkhggmlvrnplsrnsthemywisngtgnivssvnmvsrllln
rftmthrrptiekdvdlgagtrhvnaepetpnmdvi

    Sequence, based on observed residues (ATOM records): (download) 
    >5eifA (A:)
etlgekwkkklnqlsrkefdlykksgitevdrteakeglkrgetthhavsrgsaklqwfv
ernmvipegrvidlgcgrggwsyycaglkkvtevrgytkggpgheepvpmstygwnivkl
msgkdvfylppekcdtllcdigesspsptveesrtirvlkmvepwlknnqfcikvlnpym
ptviehlerlqrkhggmlvrnplsrnsthemywisngtgnivssvnmvsrlllnrftmth
rrptiekdvdlgagtr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5eifC (C:)
gtgsqgetlgekwkkklnqlsrkefdlykksgitevdrteakeglkrgetthhavsrgsa
klqwfvernmvipegrvidlgcgrggwsyycaglkkvtevrgytkggpgheepvpmstyg
wnivklmsgkdvfylppekcdtllcdigesspsptveesrtirvlkmvepwlknnqfcik
vlnpymptviehlerlqrkhggmlvrnplsrnsthemywisngtgnivssvnmvsrllln
rftmthrrptiekdvdlgagtrhvnaepetpnmdvi

    Sequence, based on observed residues (ATOM records): (download) 
    >5eifC (C:)
etlgekwkkklnqlsrkefdlykksgitevdrteakeglkrgetthhavsrgsaklqwfv
ernmvipegrvidlgcgrggwsyycaglkkvtevrgytkggpgheepvpmstygwnivkl
msgkdvfylppekcdtllcdigesspsptveesrtirvlkmvepwlknnqfcikvlnpym
ptviehlerlqrkhggmlvrnplsrnsthemywisngtgnivssvnmvsrlllnrftmth
rrptiekdvdlgagtr