PDB entry 5ehg

View 5ehg on RCSB PDB site
Description: dengue 3 ns5 methyltransferase bound to s-adenosyl methionine and molecule bf341
Class: transferase
Keywords: transferase, dengue virus, ns5 methyltransferase, fragment-based drug discovery
Deposited on 2015-10-28, released 2016-10-26
The last revision prior to the SCOPe 2.06 freeze date was dated 2016-10-26, with a file datestamp of 2016-10-21.
Experiment type: XRAY
Resolution: 2.02 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Genome polyprotein
    Species: Dengue virus type 3 (strain Philippines/H87/1956) [TaxId:408870]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27915
      • conflict (49)
    Domains in SCOPe 2.06: d5ehga1, d5ehga2
  • Chain 'C':
    Compound: Genome polyprotein
    Species: Dengue virus type 3 (strain Philippines/H87/1956) [TaxId:408870]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27915
      • conflict (49)
    Domains in SCOPe 2.06: d5ehgc1, d5ehgc2
  • Heterogens: SAM, 5O0, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5ehgA (A:)
gtgsqgetlgekwkkklnqlsrkefdlykksgitevdrteakeglkrgetthhavsrgsa
klqwfvernmvipegrvidlgcgrggwsyycaglkkvtevrgytkggpgheepvpmstyg
wnivklmsgkdvfylppekcdtllcdigesspsptveesrtirvlkmvepwlknnqfcik
vlnpymptviehlerlqrkhggmlvrnplsrnsthemywisngtgnivssvnmvsrllln
rftmthrrptiekdvdlgagtrhvnaepetpnmdvi

    Sequence, based on observed residues (ATOM records): (download) 
    >5ehgA (A:)
etlgekwkkklnqlsrkefdlykksgitevdrteakeglkrgetthhavsrgsaklqwfv
ernmvipegrvidlgcgrggwsyycaglkkvtevrgytkggpgheepvpmstygwnivkl
msgkdvfylppekcdtllcdigesspsptveesrtirvlkmvepwlknnqfcikvlnpym
ptviehlerlqrkhggmlvrnplsrnsthemywisngtgnivssvnmvsrlllnrftmth
rrptiekdvdlgagtr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5ehgC (C:)
gtgsqgetlgekwkkklnqlsrkefdlykksgitevdrteakeglkrgetthhavsrgsa
klqwfvernmvipegrvidlgcgrggwsyycaglkkvtevrgytkggpgheepvpmstyg
wnivklmsgkdvfylppekcdtllcdigesspsptveesrtirvlkmvepwlknnqfcik
vlnpymptviehlerlqrkhggmlvrnplsrnsthemywisngtgnivssvnmvsrllln
rftmthrrptiekdvdlgagtrhvnaepetpnmdvi

    Sequence, based on observed residues (ATOM records): (download) 
    >5ehgC (C:)
etlgekwkkklnqlsrkefdlykksgitevdrteakeglkrgetthhavsrgsaklqwfv
ernmvipegrvidlgcgrggwsyycaglkkvtevrgytkggpgheepvpmstygwnivkl
msgkdvfylppekcdtllcdigesspsptveesrtirvlkmvepwlknnqfcikvlnpym
ptviehlerlqrkhggmlvrnplsrnsthemywisngtgnivssvnmvsrlllnrftmth
rrptiekdvdlgagtr