PDB entry 5dx6

View 5dx6 on RCSB PDB site
Description: Acetolactate Synthase from Klebsiella pneumoniae soaked with beta-fluoropyruvate
Class: transferase
Keywords: Synthase Thiamine Diphosphate beta-fluoropyruvate, TRANSFERASE
Deposited on 2015-09-23, released 2016-09-28
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-20, with a file datestamp of 2017-09-15.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acetolactate synthase, catabolic
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: budB, ilvK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27696
      • conflict (426)
    Domains in SCOPe 2.07: d5dx6a1, d5dx6a2, d5dx6a3
  • Chain 'B':
    Compound: Acetolactate synthase, catabolic
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: budB, ilvK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27696 (20-578)
      • expression tag (14-19)
      • conflict (426)
    Domains in SCOPe 2.07: d5dx6b1, d5dx6b2, d5dx6b3, d5dx6b4
  • Heterogens: PO4, MG, 5GY, TPP, 65S, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5dx6A (A:)
mgsshhhhhhssglvprgshmdkqypvrqwahgadlvvsqleaqgvrqvfgipgakidkv
fdslldssiriipvrheanaafmaaavgritgkagvalvtsgpgcsnlitgmatansegd
pvvalggavkradkakqvhqsmdtvamfspvtkyaievtapdalaevvsnafraaeqgrp
gsafvslpqdvvdgpvsgkvlpasgapqmgaapddaidqvakliaqaknpifllglmasq
penskalrrlletshipvtstyqaagavnqdnfsrfagrvglfnnqagdrllqladlvic
igyspveyepamwnsgnatlvhidvlpayeernytpdvelvgdiagtlnklaqnidhrlv
lspqaaeilrdrqhqrelldrrgaqlnqfalhplrivramqdivnsdvtltvdmgsfhiw
iarylysfrarqvmisngqqtmgvalpwaigawlvnperkvvsvsgdggflqssmeleta
vrlkanvlhliwvdngynmvaiqeekkyqrlsgvefgpmdfkayaesfgakgfavesaea
leptlraamdvdgpavvaipvdyrdnpllmgqlhlsqil

    Sequence, based on observed residues (ATOM records): (download) 
    >5dx6A (A:)
pvrqwahgadlvvsqleaqgvrqvfgipgakidkvfdslldssiriipvrheanaafmaa
avgritgkagvalvtsgpgcsnlitgmatansegdpvvalggavkradkakmdtvamfsp
vtkyaievtapdalaevvsnafraaeqgrpgsafvslpqdvvdgpvsgkvlpapqmgaap
ddaidqvakliaqaknpifllglmasqpenskalrrlletshipvtstyqaagavnqdnf
srfagrvglfnnqagdrllqladlvicigyspveyepamwnsgnatlvhidvlpayeern
ytpdvelvgdiagtlnklaqnidhrlvlspqaaeilrdrqhqrelldrrgaqlnqfalhp
lrivramqdivnsdvtltvdmgsfhiwiarylysfrarqvmisngqqtmgvalpwaigaw
lvnperkvvsvsgdggflqssmeletavrlkanvlhliwvdngynmvaiqeekkyqrlsg
vefgpmdfkayaesfgakgfavesaealeptlraamdvdgpavvaipvdyrdnpllmgql
h

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5dx6B (B:)
mgsshhhhhhssglvprgshmdkqypvrqwahgadlvvsqleaqgvrqvfgipgakidkv
fdslldssiriipvrheanaafmaaavgritgkagvalvtsgpgcsnlitgmatansegd
pvvalggavkradkakqvhqsmdtvamfspvtkyaievtapdalaevvsnafraaeqgrp
gsafvslpqdvvdgpvsgkvlpasgapqmgaapddaidqvakliaqaknpifllglmasq
penskalrrlletshipvtstyqaagavnqdnfsrfagrvglfnnqagdrllqladlvic
igyspveyepamwnsgnatlvhidvlpayeernytpdvelvgdiagtlnklaqnidhrlv
lspqaaeilrdrqhqrelldrrgaqlnqfalhplrivramqdivnsdvtltvdmgsfhiw
iarylysfrarqvmisngqqtmgvalpwaigawlvnperkvvsvsgdggflqssmeleta
vrlkanvlhliwvdngynmvaiqeekkyqrlsgvefgpmdfkayaesfgakgfavesaea
leptlraamdvdgpavvaipvdyrdnpllmgqlhlsqil

    Sequence, based on observed residues (ATOM records): (download) 
    >5dx6B (B:)
vprgshmdkqypvrqwahgadlvvsqleaqgvrqvfgipgakidkvfdslldssiriipv
rheanaafmaaavgritgkagvalvtsgpgcsnlitgmatansegdpvvalggavkradk
akqvhqsmdtvamfspvtkyaievtapdalaevvsnafraaeqgrpgsafvslpqdvvdg
pvsgkvlpasgapqmgaapddaidqvakliaqaknpifllglmasqpenskalrrllets
hipvtstyqaagavnqdnfsrfagrvglfnnqagdrllqladlvicigyspveyepamwn
sgnatlvhidvlpayeernytpdvelvgdiagtlnklaqnidhrlvlspqaaeilrdrqh
qrelnqfalhplrivramqdivnsdvtltvdmgsfhiwiarylysfrarqvmisngqqtm
gvalpwaigawlvnperkvvsvsgdggflqssmeletavrlkanvlhliwvdngynmvai
qeekkyqrlsgvefgpmdfkayaesfgakgfavesaealeptlraamdvdgpavvaipvd
yrdnpllmgqlhlsqil