PDB entry 5dp7

View 5dp7 on RCSB PDB site
Description: Crystal Structure of EV71 3C Proteinase in complex with compound 5
Class: hydrolase/hydrolase inhibitor
Keywords: Hand, foot and mouth disease, 3C proteinase, peptidomimetics, drug design, rupintrivir, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2015-09-12, released 2016-03-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-04-06, with a file datestamp of 2016-04-01.
Experiment type: XRAY
Resolution: 2.08 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3C proteinase
    Species: ENTEROVIRUS A71 [TaxId:39054]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A9XG43 (1-End)
      • initiating methionine (0)
    Domains in SCOPe 2.08: d5dp7a1, d5dp7a2
  • Heterogens: 5EC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5dp7A (A:)
    mgpsldfalsllrrnvrqvqtdqghftmlgvrdrlavlprhsqpgktiwiehklvnilda
    velvdeqgvnleltlitldtnekfrditkfipenistasdatlvintehmpsmfvpvgdv
    vqygflnlsgkpthrtmmynfptkagqcggvvtsvgkvigihiggngrqgfcaglkrsyf
    aseqlehhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >5dp7A (A:)
    mgpsldfalsllrrnvrqvqtdqghftmlgvrdrlavlprhsqpgktiwiehklvnilda
    velvdeqgvnleltlitldtnekfrditkfipenistasdatlvintehmpsmfvpvgdv
    vqygflnlsgkpthrtmmynfptkagqcggvvtsvgkvigihiggngrqgfcaglkrsyf
    a