PDB entry 5dp7
View 5dp7 on RCSB PDB site
Description: Crystal Structure of EV71 3C Proteinase in complex with compound 5
Class: hydrolase/hydrolase inhibitor
Keywords: Hand, foot and mouth disease, 3C proteinase, peptidomimetics, drug design, rupintrivir, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on
2015-09-12, released
2016-03-30
The last revision prior to the SCOPe 2.08 freeze date was dated
2016-04-06, with a file datestamp of
2016-04-01.
Experiment type: XRAY
Resolution: 2.08 Å
R-factor: N/A
AEROSPACI score: 0.28
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: 3C proteinase
Species: ENTEROVIRUS A71 [TaxId:39054]
Database cross-references and differences (RAF-indexed):
- Uniprot A9XG43 (1-End)
- initiating methionine (0)
Domains in SCOPe 2.08: d5dp7a1, d5dp7a2 - Heterogens: 5EC, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5dp7A (A:)
mgpsldfalsllrrnvrqvqtdqghftmlgvrdrlavlprhsqpgktiwiehklvnilda
velvdeqgvnleltlitldtnekfrditkfipenistasdatlvintehmpsmfvpvgdv
vqygflnlsgkpthrtmmynfptkagqcggvvtsvgkvigihiggngrqgfcaglkrsyf
aseqlehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>5dp7A (A:)
mgpsldfalsllrrnvrqvqtdqghftmlgvrdrlavlprhsqpgktiwiehklvnilda
velvdeqgvnleltlitldtnekfrditkfipenistasdatlvintehmpsmfvpvgdv
vqygflnlsgkpthrtmmynfptkagqcggvvtsvgkvigihiggngrqgfcaglkrsyf
a