PDB entry 5dif

View 5dif on RCSB PDB site
Description: Crystal Structure of CPEB4 NES Peptide in complex with CRM1-Ran-RanBP1
Class: transport protein
Keywords: Peptides, HEAT repeat, Nuclear Export Signal, Exportin-1, Nuclear Transport, TRANSPORT PROTEIN
Deposited on 2015-08-31, released 2015-09-16
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-10-21, with a file datestamp of 2015-10-16.
Experiment type: XRAY
Resolution: 2.09 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GTP-binding nuclear protein ran
    Species: Homo sapiens [TaxId:9606]
    Gene: RAN, ARA24, OK/SW-cl.81
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5difa_
  • Chain 'B':
    Compound: Ran-specific GTPase-activating protein 1
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: YRB1, CST20, HTN1, SFO1, YDR002W, YD8119.08
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5difb_
  • Chain 'C':
    Compound: Exportin-1
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: CRM1, KAP124, XPO1, YGR218W, G8514
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30822 (3-End)
      • expression tag (1-2)
      • engineered mutation (502)
      • engineered mutation (504-506)
      • engineered mutation (987)
  • Chain 'D':
    Compound: Cytoplasmic polyadenylation element-binding protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: CPEB4
    Database cross-references and differences (RAF-indexed):
    • PDB 5DIF (Start-18)
  • Heterogens: GNP, MG, GOL, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5difA (A:)
metgsshhhhhhssglprgshmaaqgepqvqfklvlvgdggtgkttfvkrhltgefekky
vatlgvevhplvfhtnrgpikfnvwdtagqekfgglrdgyyiqaqcaiimfdvtsrvtyk
nvpnwhrdlvrvcenipivlcgnkvdikdrkvkaksivfhrkknlqyydisaksnynfek
pflwlarkligdpnlefvampalappevvmdpalaaqyehdlevaqttalpdedddl

    Sequence, based on observed residues (ATOM records): (download) 
    >5difA (A:)
qvqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpikfnvwdta
gqekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlcgnkvdik
drkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlefvampalappev
vmdpalaaqyehdlevaqttalpdedddl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5difB (B:)
ggsdihfepvvhlekvdvktmeedeevlykvraklfrfdadakewkergtgdckflknkk
tnkvrilmrrdktlkicanhiiapeytlkpnvgsdrswvyactadiaegeaeaftfairf
gskenadkfkeefekaqeinkka

    Sequence, based on observed residues (ATOM records): (download) 
    >5difB (B:)
ihfepvvtmeedeevlykvraklfrfdadakewkergtgdckflknkktnkvrilmrrdk
tlkicanhiiapeytlkpnvgsdrswvyactadiaegeaeaftfairfgskenadkfkee
fekaqeinkk

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.