PDB entry 5d7j

View 5d7j on RCSB PDB site
Description: Structure of human MR1-5-OP-RU in complex with human MAIT M33.64(Y95alphaF) TCR
Class: immune system
Keywords: Receptor, Antigen, IMMUNE SYSTEM
Deposited on 2015-08-14, released 2016-01-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-02-10, with a file datestamp of 2016-02-05.
Experiment type: XRAY
Resolution: 1.97 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: M33.64 TCR Alpha Chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TRAV/TRAV
    Database cross-references and differences (RAF-indexed):
    • PDB 5D7J
    Domains in SCOPe 2.07: d5d7ja1, d5d7ja2
  • Chain 'B':
    Compound: M33.64 TCR Beta Chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TRBV/TRBC
    Database cross-references and differences (RAF-indexed):
    • PDB 5D7J
    Domains in SCOPe 2.07: d5d7jb1, d5d7jb2
  • Chain 'C':
    Compound: Major histocompatibility complex class I-related gene protein
    Species: Homo sapiens [TaxId:9606]
    Gene: MR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95460 (1-End)
      • conflict (261)
    Domains in SCOPe 2.07: d5d7jc1, d5d7jc2
  • Chain 'D':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5d7jd_
  • Chain 'E':
    Compound: Major histocompatibility complex class I-related gene protein
    Species: Homo sapiens [TaxId:9606]
    Gene: MR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95460 (1-End)
      • conflict (261)
    Domains in SCOPe 2.07: d5d7je1, d5d7je2
  • Chain 'F':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-End)
      • initiating methionine (0)
    Domains in SCOPe 2.07: d5d7jf1, d5d7jf2
  • Chain 'G':
    Compound: M33.64 TCR Alpha Chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TRAV/TRAV
    Database cross-references and differences (RAF-indexed):
    • PDB 5D7J
    Domains in SCOPe 2.07: d5d7jg1, d5d7jg2
  • Chain 'H':
    Compound: M33.64 TCR Beta Chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TRBV/TRBC
    Database cross-references and differences (RAF-indexed):
    • PDB 5D7J (Start-244)
    Domains in SCOPe 2.07: d5d7jh1, d5d7jh2
  • Heterogens: GOL, 2LJ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5d7jA (A:)
    mgqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgr
    fssflsrskgysylllkelqmkdsasylcavmdsnfqliwgagtkliikpdiqnpdpavy
    qlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksd
    facanafnnsiipedtffpspess
    

    Sequence, based on observed residues (ATOM records): (download)
    >5d7jA (A:)
    gqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrf
    ssflsrskgysylllkelqmkdsasylcavmdsnfqliwgagtkliikpdiqnpdpavyq
    lrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdf
    acanafnnsiipedtffpsp
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5d7jB (B:)
    miagitqaptsqilaagrrmtlrctqdmrhnamywyrqdlglglrlihysntagttgkge
    vpdgysvsrantddfpltlasavpsqtsvyfcasseaggntgelffgegsrltvledlkn
    vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
    qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
    wgrad
    

    Sequence, based on observed residues (ATOM records): (download)
    >5d7jB (B:)
    gitqaptsqilaagrrmtlrctqdmrhnamywyrqdlglglrlihysntagttgkgevpd
    gysvsrantddfpltlasavpsqtsvyfcasseaggntgelffgegsrltvledlknvfp
    pevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpa
    lndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgr
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >5d7jC (C:)
    mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
    erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
    lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
    epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
    awasieldpqssnlyschvehsgvhmvlqvp
    

    Sequence, based on observed residues (ATOM records): (download)
    >5d7jC (C:)
    rthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhwe
    rytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdfl
    ifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrte
    pplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyqa
    wasiellyschvehsgvhmvlqv
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >5d7jD (D:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

    Sequence, based on observed residues (ATOM records): (download)
    >5d7jD (D:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrd
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >5d7jE (E:)
    mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
    erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
    lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
    epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
    awasieldpqssnlyschvehsgvhmvlqvp
    

    Sequence, based on observed residues (ATOM records): (download)
    >5d7jE (E:)
    rthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhwe
    rytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdfl
    ifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrte
    pplvrvnrkgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyqawasi
    eldpqssnlyschvehsgvhmvlqv
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >5d7jF (F:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

    Sequence, based on observed residues (ATOM records): (download)
    >5d7jF (F:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdr
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >5d7jG (G:)
    mgqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgr
    fssflsrskgysylllkelqmkdsasylcavmdsnfqliwgagtkliikpdiqnpdpavy
    qlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksd
    facanafnnsiipedtffpspess
    

    Sequence, based on observed residues (ATOM records): (download)
    >5d7jG (G:)
    gqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrf
    ssflsrskgysylllkelqmkdsasylcavmdsnfqliwgagtkliikpdiqnpdpavyq
    lrdskssdvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdfac
    anafnnsiipedtffp
    

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >5d7jH (H:)
    miagitqaptsqilaagrrmtlrctqdmrhnamywyrqdlglglrlihysntagttgkge
    vpdgysvsrantddfpltlasavpsqtsvyfcasseaggntgelffgegsrltvledlkn
    vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
    qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
    wgrad
    

    Sequence, based on observed residues (ATOM records): (download)
    >5d7jH (H:)
    gitqaptsqilaagrrmtlrctqdmrhnamywyrqdlglglrlihysntagttgkgevpd
    gysvsrantddfpltlasavpsqtsvyfcasseaggntgelffgegsrltvledlknvfp
    pevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpa
    lndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgr
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