PDB entry 5d24

View 5d24 on RCSB PDB site
Description: First bromodomain of BRD4 bound to inhibitor XD26
Class: transcription
Keywords: Gene regulation, Inhibitor, bromodomain, transcription
Deposited on 2015-08-05, released 2016-01-20
The last revision prior to the SCOPe 2.06 freeze date was dated 2016-03-09, with a file datestamp of 2016-03-04.
No data on structure quality are available

Chains and heterogens:

• Chain 'A':
  Compound: Bromodomain-containing protein 4
  Species: Homo sapiens [TaxId:9606]
  Gene: BRD4, HUNK1
  Database cross-references and differences (RAF-indexed):
  • Uniprot O60885 (0-125)
    • engineered mutation (0)
  Domains in SCOPe 2.06: d5d24a_
• Heterogens: L26, EDO, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >5d24A (A:)
  mnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiik
  tpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkin
  elptee