PDB entry 5d1j

View 5d1j on RCSB PDB site
Description: crystal structure of cyclin-dependent kinase 2 (cdk2-wt) complex with n-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl] methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide (bms-387032)
Class: transferase/transferase inhibitor
Keywords: KINASE, MITOSIS, CELL CYCLE, TRANSFERASE-TRANSFERASE INHIBIT COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2015-08-04, released 2015-08-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cyclin-dependent kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2, CDKN2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5d1ja_
  • Heterogens: 56H, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5d1jA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >5d1jA (A:)
    menfqkvekigeygvvykarnkltgevvalkkireisllkelnhpnivklldvihtenkl
    ylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlkpqnllin
    tegaikladfvtlwyrapeillgckyystavdiwslgcifaemvtrralfpgdseidqlf
    rifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrsllsqmlhydpnk
    risakaalahpffqdvtkpvphlrl