PDB entry 5caw

View 5caw on RCSB PDB site
Description: Structure of Pediculus humanus Parkin bound to phospho-ubiquitin
Class: signaling protein
Keywords: ubiquitin, Parkin, PINK1, phospho-ubiquitin, Parkinson's disease, E3 ligase, RBR domain, mitophagy, cell signalling, signaling protein
Deposited on 2015-06-30, released 2015-07-22
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-08-26, with a file datestamp of 2015-08-21.
Experiment type: XRAY
Resolution: 2.62 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: E3 ubiquitin-protein ligase parkin
    Species: Pediculus humanus subsp. corporis [TaxId:121224]
    Gene: Phum_PHUM233570
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Polyubiquitin-B
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0CG47 (0-75)
      • engineered mutation (75)
    Domains in SCOPe 2.06: d5cawb_
  • Chain 'C':
    Compound: E3 ubiquitin-protein ligase parkin
    Species: Pediculus humanus subsp. corporis [TaxId:121224]
    Gene: Phum_PHUM233570
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Polyubiquitin-B
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0CG47 (0-75)
      • engineered mutation (75)
    Domains in SCOPe 2.06: d5cawd_
  • Heterogens: ZN, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5cawB (B:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrgx
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5cawD (D:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrgx