PDB entry 5bww

View 5bww on RCSB PDB site
Description: x-ray crystal structure at 1.82a resolution of human mitochondrial branched chain aminotransferase (bcatm) complexed with a pyrrolidine amide compound and an internal aldimine linked plp cofactor.
Class: transferase
Keywords: fold type IV, transferase
Deposited on 2015-06-08, released 2015-07-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-06-12, with a file datestamp of 2019-06-07.
Experiment type: XRAY
Resolution: 1.82 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Branched-chain-amino-acid aminotransferase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: BCAT2, BCATM, BCT2, ECA40
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5bwwa_
  • Chain 'B':
    Compound: Branched-chain-amino-acid aminotransferase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: BCAT2, BCATM, BCT2, ECA40
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5bwwb_
  • Heterogens: PLP, 4W6, EDO, CL, GOL, DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5bwwA (A:)
gshmasssfkaadlqlemtqkphkkpgpgeplvfgktftdhmlmvewndkgwgqpriqpf
qnltlhpassslhyslqlfegmkafkgkdqqvrlfrpwlnmdrmlrsamrlclpsfdkle
llecirrlievdkdwvpdaagtslyvrpvlignepslgvsqptrallfvilcpvgayfpg
gsvtpvslladpafirawvggvgnyklggnygptvlvqqealkrgceqvlwlygpdhqlt
evgtmnifvywthedgvlelvtpplngvilpgvvrqslldmaqtwgefrvvertitmkql
lraleegrvrevfgsgtacqvcpvhrilykdrnlhiptmengpelilrfqkelkeiqygi
rahewmfpv

    Sequence, based on observed residues (ATOM records): (download) 
    >5bwwA (A:)
ssfkaadlqlemtqkphkkpgplvfgktftdhmlmvewndkgwgqpriqpfqnltlhpas
sslhyslqlfegmkafkgkdqqvrlfrpwlnmdrmlrsamrlclpsfdklellecirrli
evdkdwvpdaagtslyvrpvlignepslgvsqptrallfvilcpvgvtpvslladpafir
awvggvgnyklggnygptvlvqqealkrgceqvlwlygpdhqltevgtmnifvywthedg
vlelvtpplngvilpgvvrqslldmaqtwgefrvvertitmkqllraleegrvrevfgsg
tacqvcpvhrilykdrnlhiptmengpelilrfqkelkeiqygirahewmfpv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5bwwB (B:)
gshmasssfkaadlqlemtqkphkkpgpgeplvfgktftdhmlmvewndkgwgqpriqpf
qnltlhpassslhyslqlfegmkafkgkdqqvrlfrpwlnmdrmlrsamrlclpsfdkle
llecirrlievdkdwvpdaagtslyvrpvlignepslgvsqptrallfvilcpvgayfpg
gsvtpvslladpafirawvggvgnyklggnygptvlvqqealkrgceqvlwlygpdhqlt
evgtmnifvywthedgvlelvtpplngvilpgvvrqslldmaqtwgefrvvertitmkql
lraleegrvrevfgsgtacqvcpvhrilykdrnlhiptmengpelilrfqkelkeiqygi
rahewmfpv

    Sequence, based on observed residues (ATOM records): (download) 
    >5bwwB (B:)
sssfkaadlqlemtqkphkkpglvfgktftdhmlmvewndkgwgqpriqpfqnltlhpas
sslhyslqlfegmkafkgkdqqvrlfrpwlnmdrmlrsamrlclpsfdklellecirrli
evdkdwvpdaagtslyvrpvlignepslgvsqptrallfvilcpvgvtpvslladpafir
awvggvgnyklggnygptvlvqqealkrgceqvlwlygpdhqltevgtmnifvywthedg
vlelvtpplngvilpgvvrqslldmaqtwgefrvvertitmkqllraleegrvrevfgsg
tacqvcpvhrilykdrnlhiptmengpelilrfqkelkeiqygirahewmfpv