PDB entry 5bnx

View 5bnx on RCSB PDB site
Description: Crystal structure of Human MCM2 HBD and ASF1b chaperoning a histone H3.3-H4 dimer
Class: chaperone/DNA binding protein
Keywords: DNA replication, MCM2, ASF1, H3.3-H4 dimer, CHAPERONE-DNA BINDING PROTEIN complex
Deposited on 2015-05-26, released 2015-06-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-08-19, with a file datestamp of 2015-08-14.
Experiment type: XRAY
Resolution: 2.31 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone H3.3
    Species: Homo sapiens [TaxId:9606]
    Gene: H3F3A, H3.3A, H3F3, PP781, H3F3B, H3.3B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5bnxa_
  • Chain 'B':
    Compound: histone h4
    Species: Homo sapiens [TaxId:9606]
    Gene: HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5bnxb_
  • Chain 'C':
    Compound: DNA replication licensing factor mcm2
    Species: Homo sapiens [TaxId:9606]
    Gene: MCM2, BM28, CCNL1, CDCL1, KIAA0030
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Histone chaperone ASF1B
    Species: Homo sapiens [TaxId:9606]
    Gene: ASF1B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5bnxd_
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5bnxA (A:)
stellirklpfqrlvreiaqdfktdlrfqsaaigalqeaseaylvglfedtnlcaihakr
vtimpkdiqlarrirgera

    Sequence, based on observed residues (ATOM records): (download) 
    >5bnxA (A:)
tellirklpfqrlvreiaqdfktdlrfqsaaigalqeaseaylvglfedtnlcaihakrv
timpkdiqlarrirger

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5bnxB (B:)
sgrgkggkglgkggakrhrkvlrdniqgitkpairrlarrggvkrisgliyeetrgvlkv
flenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg

    Sequence, based on observed residues (ATOM records): (download) 
    >5bnxB (B:)
rhrkvlrdniqgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtyteha
krktvtamdvvyalkrqgrtlygfgg

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5bnxD (D:)
makvsvlnvavlenpspfhspfrfeisfecsealaddlewkiiyvgsaeseefdqildsv
lvgpvpagrhmfvfqadapnpslipetdavgvtvvlitctyhgqefirvgyyvnneylnp
elrenppmkpdfsqlqrnilasnprvtrfhinwdnnmd

    Sequence, based on observed residues (ATOM records): (download) 
    >5bnxD (D:)
makvsvlnvavlenpspfhspfrfeisfecsealaddlewkiiyvgsaeseefdqildsv
lvgpvpagrhmfvfqadapnpslipetdavgvtvvlitctyhgqefirvgyyvnneylnp
elrenppmkpdfsqlqrnilasnprvtrfhinwd