PDB entry 5anm

View 5anm on RCSB PDB site
Description: Crystal structure of IgE Fc in complex with a neutralizing antibody
Class: immune system
Keywords: immune system, therapeutic antibody, igg, ige, asthma
Deposited on 2015-09-07, released 2015-09-30
The last revision prior to the SCOPe 2.05 freeze date was dated 2015-09-30, with a file datestamp of 2015-09-25.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: immunoglobulin g
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5ANM
    Domains in SCOPe 2.05: d5anma1, d5anma2
  • Chain 'B':
    Compound: immunoglobulin g
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5ANM (0-End)
  • Chain 'C':
    Compound: immunoglobulin g
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5ANM
    Domains in SCOPe 2.05: d5anmc1, d5anmc2
  • Chain 'D':
    Compound: immunoglobulin g
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5ANM (0-End)
  • Chain 'E':
    Compound: ig epsilon chain c region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d5anme1, d5anme2
  • Chain 'F':
    Compound: ig epsilon chain c region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d5anmf1, d5anmf2
  • Chain 'G':
    Compound: ig epsilon chain c region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d5anmg1, d5anmg2
  • Chain 'H':
    Compound: immunoglobulin g
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5ANM (0-End)
  • Chain 'L':
    Compound: immunoglobulin g
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5ANM
    Domains in SCOPe 2.05: d5anml1, d5anml2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5anmA (A:)
qsvltqppsvsgapgqrvtisctgsssnigagydvhwyqqlpgtapklliydnfnrpsgv
pdrfsgsksgtsaslaitglqaedeadyycqsydsptltspfgtgtkltvlgqpkaapsv
tlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaas
sylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >5anmA (A:)
svltqppsvsgapgqrvtisctgsssnigagydvhwyqqlpgtapklliydnfnrpsgvp
drfsgsksgtsaslaitglqaedeadyycqsydsptltspfgtgtkltvlgqpkaapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvapt

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5anmC (C:)
qsvltqppsvsgapgqrvtisctgsssnigagydvhwyqqlpgtapklliydnfnrpsgv
pdrfsgsksgtsaslaitglqaedeadyycqsydsptltspfgtgtkltvlgqpkaapsv
tlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaas
sylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >5anmC (C:)
svltqppsvsgapgqrvtisctgsssnigagydvhwyqqlpgtapklliydnfnrpsgvp
drfsgsksgtsaslaitglqaedeadyycqsydsptltspfgtgtkltvlgqpkaapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvapt

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5anmE (E:)
adpcdsnprgvsaylsrpspfdlfirksptitclvvdlapskgtvnltwsrasgkpvnhs
trkeekqrngtltvtstlpvgtrdwiegetyqcrvthphlpralmrsttktsgpraapev
yafatpewpgsrdkrtlacliqnfmpedisvqwlhnevqlpdarhsttqprktkgsgffv
fsrlevtraeweqkdeficravheaaspsqtvqravsvnpgkdykddddkaahhhhhhhh
hh

    Sequence, based on observed residues (ATOM records): (download) 
    >5anmE (E:)
vsaylsrpspfdlfirksptitclvvdlapskgtvnltwsrasgkpvnhstrkeekqrng
tltvtstlpvgtrdwiegetyqcrvthphlpralmrsttktsgpraapevyafatpewpg
srdkrtlacliqnfmpedisvqwlhnevqlpdarhsttqprktkgffvfsrlevtraewe
qkdeficravheaaspsqtvqravsv

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >5anmF (F:)
adpcdsnprgvsaylsrpspfdlfirksptitclvvdlapskgtvnltwsrasgkpvnhs
trkeekqrngtltvtstlpvgtrdwiegetyqcrvthphlpralmrsttktsgpraapev
yafatpewpgsrdkrtlacliqnfmpedisvqwlhnevqlpdarhsttqprktkgsgffv
fsrlevtraeweqkdeficravheaaspsqtvqravsvnpgkdykddddkaahhhhhhhh
hh

    Sequence, based on observed residues (ATOM records): (download) 
    >5anmF (F:)
gvsaylsrpspfdlfirksptitclvvdlapskgtvnltwsrasgkpvnhstrkeekqrn
gtltvtstlpvgtrdwiegetyqcrvthppralmrsttktsgpraapevyafatppgsrd
krtlacliqnfmpedisvqwlhnevqlpdarhsttqprktkgsgffvfsrlevtraeweq
kdeficravheaaspsqtvqravsvnpg

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >5anmG (G:)
adpcdsnprgvsaylsrpspfdlfirksptitclvvdlapskgtvnltwsrasgkpvnhs
trkeekqrngtltvtstlpvgtrdwiegetyqcrvthphlpralmrsttktsgpraapev
yafatpewpgsrdkrtlacliqnfmpedisvqwlhnevqlpdarhsttqprktkgsgffv
fsrlevtraeweqkdeficravheaaspsqtvqravsvnpgkdykddddkaahhhhhhhh
hh

    Sequence, based on observed residues (ATOM records): (download) 
    >5anmG (G:)
gvsaylsrpspfdlfirksptitclvvdlapskgtvnltwsrasgkpvnhstrkeekqrn
gtltvtstlpvgtrdwiegetyqcrvthphlpralmrsttktsgpraapevyafatpewp
gsrdkrtlacliqnfmpedisvqwlhnevqlpdarhsttqprktkgsgffvfsrlevtra
eweqkdeficravheaaspsqtvqravsvnp

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >5anmL (L:)
qsvltqppsvsgapgqrvtisctgsssnigagydvhwyqqlpgtapklliydnfnrpsgv
pdrfsgsksgtsaslaitglqaedeadyycqsydsptltspfgtgtkltvlgqpkaapsv
tlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaas
sylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >5anmL (L:)
vltqppsvsgapgqrvtisctgsssnigagydvhwyqqlpgtapklliydnfnrpsgvpd
rfsgsksgtsaslaitglqaedeadyycqsydsptltspfgtgtkltvpkaapsvtlfpp
satlvclisdavtvawkadsspvkagvetttpskqaassylsltpeshrsyscqvthegs
tvektvapt