PDB entry 5aiu

View 5aiu on RCSB PDB site
Description: A complex of RNF4-RING domain, Ubc13-Ub (isopeptide crosslink)
Class: ligase/signaling protein
Keywords: ligase-signaling protein complex, complex, fusion protein
Deposited on 2015-02-17, released 2015-07-08
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-08-19, with a file datestamp of 2015-08-14.
Experiment type: XRAY
Resolution: 2.21 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: E3 ubiquitin-protein ligase RNF4
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O88846 (69-132)
      • linker (68)
  • Chain 'B':
    Compound: Ubiquitin-conjugating enzyme E2 N
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61088
      • engineered mutation (88)
      • engineered mutation (93)
    Domains in SCOPe 2.06: d5aiub_
  • Chain 'C':
    Compound: Polyubiquitin-C
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5aiuc_
  • Chain 'E':
    Compound: Ubiquitin-conjugating enzyme E2 N
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61088
      • engineered mutation (88)
      • engineered mutation (93)
    Domains in SCOPe 2.06: d5aiue_
  • Chain 'F':
    Compound: Polyubiquitin-C
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5aiuf_
  • Heterogens: ZN, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5aiuB (B:)
gamaglprriiketqrllaepvpgikaepdesnaryfhvviagpqdspfeggtfklelfl
peeypmaapkvrfmtkiyhpnvdklgrikldiladkwspalqirtvllsiqallsapnpd
dplandvaeqwktneaqaietarawtrlyamnni

    Sequence, based on observed residues (ATOM records): (download) 
    >5aiuB (B:)
aglprriiketqrllaepvpgikaepdesnaryfhvviagpqdspfeggtfklelflpee
ypmaapkvrfmtkiyhpnvdklgrikldiladkwspalqirtvllsiqallsapnpddpl
andvaeqwktneaqaietarawtrlyamnn

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5aiuC (C:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrgg

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5aiuE (E:)
gamaglprriiketqrllaepvpgikaepdesnaryfhvviagpqdspfeggtfklelfl
peeypmaapkvrfmtkiyhpnvdklgrikldiladkwspalqirtvllsiqallsapnpd
dplandvaeqwktneaqaietarawtrlyamnni

    Sequence, based on observed residues (ATOM records): (download) 
    >5aiuE (E:)
aglprriiketqrllaepvpgikaepdesnaryfhvviagpqdspfeggtfklelflpee
ypmaapkvrfmtkiyhpnvdklgrikldiladkwspalqirtvllsiqallsapnpddpl
andvaeqwktneaqaietarawtrlyamnn

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5aiuF (F:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrgg