PDB entry 4zft

View 4zft on RCSB PDB site
Description: Catalytic domain of Sst2 F403W mutant bound to ubiquitin
Class: hydrolase
Keywords: helix-beta-helix sandwich, ubiquitin, Zinc metalloprotease, endosome, HYDROLASE
Deposited on 2015-04-21, released 2015-10-14
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-10-14, with a file datestamp of 2015-10-09.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: AMSH-like protease sst2
    Species: Schizosaccharomyces pombe [TaxId:284812]
    Gene: sst2, SPAC19B12.10
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9P371
      • engineered mutation (164)
  • Chain 'B':
    Compound: Polyubiquitin-B
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0CG47 (5-80)
      • expression tag (3-4)
    Domains in SCOPe 2.06: d4zftb1, d4zftb2
  • Chain 'C':
    Compound: AMSH-like protease sst2
    Species: Schizosaccharomyces pombe [TaxId:284812]
    Gene: sst2, SPAC19B12.10
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9P371
      • engineered mutation (164)
  • Chain 'D':
    Compound: Polyubiquitin-B
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0CG47 (5-80)
      • expression tag (4)
    Domains in SCOPe 2.06: d4zftd1, d4zftd2
  • Heterogens: ZN, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4zftB (B:)
gplgsmqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrt
lsdyniqkestlhlvlrlrgg

    Sequence, based on observed residues (ATOM records): (download) 
    >4zftB (B:)
gsmqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsd
yniqkestlhlvlrlrgg

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4zftD (D:)
gplgsmqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrt
lsdyniqkestlhlvlrlrgg

    Sequence, based on observed residues (ATOM records): (download) 
    >4zftD (D:)
smqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdy
niqkestlhlvlrlrgg