PDB entry 4zca

View 4zca on RCSB PDB site
Description: Eg5 motor domain mutant Y231F
Class: motor protein
Keywords: Kinesin, mitosis, ATPase, MOTOR PROTEIN
Deposited on 2015-04-15, released 2016-06-22
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-06-22, with a file datestamp of 2016-06-17.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Kinesin-like protein KIF11
    Species: Homo sapiens [TaxId:9606]
    Gene: KIF11, EG5, KNSL1, TRIP5
    Database cross-references and differences (RAF-indexed):
    • Uniprot P52732
      • engineered mutation (230)
    Domains in SCOPe 2.07: d4zcaa_
  • Chain 'B':
    Compound: Kinesin-like protein KIF11
    Species: Homo sapiens [TaxId:9606]
    Gene: KIF11, EG5, KNSL1, TRIP5
    Database cross-references and differences (RAF-indexed):
    • Uniprot P52732
      • engineered mutation (230)
    Domains in SCOPe 2.07: d4zcab_
  • Heterogens: ADP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4zcaA (A:)
    masqpnssakkkeekgkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladk
    ssrktytfdmvfgastkqidvyrsvvcpildevimgynctifaygqtgtgktftmegers
    pneeytweedplagiiprtlhqifekltdngtefsvkvslleiyneelfdllnpssdvse
    rlqmfddprnkrgviikgleeitvhnkdevyqilekgaakrttaatlmnafssrshsvfs
    vtihmkettidgeelvkigklnlvdlagsenigrsgavdkrareagninqslltlgrvit
    alvertphvpyreskltrilqdslggrtrtsiiatispaslnleetlstleyahraknil
    nkpevnqkl
    

    Sequence, based on observed residues (ATOM records): (download)
    >4zcaA (A:)
    gkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfgas
    tkqidvyrsvvcpildevimgynctifaygqtgtgktftmegeytweedplagiiprtlh
    qifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgviikglee
    itvhnkdevyqilekgaakrttaatlmnafssrshsvfsvtihmkettidgeelvkigkl
    nlvdlagserareagninqslltlgrvitalvertphvpyreskltrilqdslggrtrts
    iiatispaslnleetlstleyahraknilnkpev
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4zcaB (B:)
    masqpnssakkkeekgkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladk
    ssrktytfdmvfgastkqidvyrsvvcpildevimgynctifaygqtgtgktftmegers
    pneeytweedplagiiprtlhqifekltdngtefsvkvslleiyneelfdllnpssdvse
    rlqmfddprnkrgviikgleeitvhnkdevyqilekgaakrttaatlmnafssrshsvfs
    vtihmkettidgeelvkigklnlvdlagsenigrsgavdkrareagninqslltlgrvit
    alvertphvpyreskltrilqdslggrtrtsiiatispaslnleetlstleyahraknil
    nkpevnqkl
    

    Sequence, based on observed residues (ATOM records): (download)
    >4zcaB (B:)
    gkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfgas
    tkqidvyrsvvcpildevimgynctifaygqtgtgktftmegeytweedplagiiprtlh
    qifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgviikglee
    itvhnkdevyqilekgaakrttaatlmnafssrshsvfsvtihmkettidgeelvkigkl
    nlvdlagsenignqslltlgrvitalvertphvpyreskltrilqdslggrtrtsiiati
    spaslnleetlstleyahraknilnkpev