PDB entry 4z9l

View 4z9l on RCSB PDB site
Description: the structure of jnk3 in complex with an imidazole-pyrimidine inhibitor
Class: transferase/inhibitor
Keywords: map kinase, apoptosis, inhibition, transferase
Deposited on 2015-04-10, released 2015-05-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-05-06, with a file datestamp of 2015-05-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 10
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK10, JNK3, JNK3A, PRKM10, SAPK1B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4z9la_
  • Heterogens: ANP, 880, UNX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4z9lA (A:)
maskskvdnqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsr
pfqnqthakrayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqvi
qmeldhermsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagts
fmmtpyvvtryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvie
qlgtpcpefmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardlls
kmlvidpakrisvddalqhpyinvwydpaeveapppqiydkqlderehtieewkeliyke
vmns

    Sequence, based on observed residues (ATOM records): (download) 
    >4z9lA (A:)
dnqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqth
akrayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldhe
rmsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglsfmmvtryyrapev
ilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpefmkklqptv
rnyvenrpkyagltfpklfpdslfdsehnklkasqardllskmlvidpakrisvddalqh
pyinvwydpaeveappphtieewkeliykevmn