PDB entry 4z6i

View 4z6i on RCSB PDB site
Description: Crystal structure of BRD9 bromodomain in complex with a substituted valerolactam quinolone ligand
Class: transcription
Keywords: lysine-acetylated histone binding, chromatin regulator, transcription, Bromodomain, Structural Genomics, Structural Genomics Consortium, SGC
Deposited on 2015-04-05, released 2015-05-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-05-20, with a file datestamp of 2015-05-15.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 9
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD9, UNQ3040/PRO9856
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4z6ia_
  • Chain 'B':
    Compound: Bromodomain-containing protein 9
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD9, UNQ3040/PRO9856
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4z6ib_
  • Heterogens: 4L3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4z6iA (A:)
smlklsaenestpiqqllehflrqlqrkdphgffafpvtdaiapgysmiikhpmdfgtmk
dkivaneyksvtefkadfklmcdnamtynrpdtvyyklakkilhagfkmmskerllalkr
sms

    Sequence, based on observed residues (ATOM records): (download) 
    >4z6iA (A:)
stpiqqllehflrqlqrkdphgffafpvtdaiapgysmiikhpmdfgtmkdkivaneyks
vtefkadfklmcdnamtynrpdtvyyklakkilhagfkmmskerllalkrsms

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4z6iB (B:)
smlklsaenestpiqqllehflrqlqrkdphgffafpvtdaiapgysmiikhpmdfgtmk
dkivaneyksvtefkadfklmcdnamtynrpdtvyyklakkilhagfkmmskerllalkr
sms

    Sequence, based on observed residues (ATOM records): (download) 
    >4z6iB (B:)
stpiqqllehflrqlqrkdphgffafpvtdaiapgysmiikhpmdfgtmkdkivaneyks
vtefkadfklmcdnamtynrpdtvyyklakkilhagfkmmskerllalkrsms