PDB entry 4z2w

View 4z2w on RCSB PDB site
Description: Factor Inhibiting HIF in Complex with Fe, and Alpha-Ketoglutarate
Class: oxidoreductase
Keywords: Hypoxia Inducible Factor, Factor Inhibiting HIF, Oxygenase, Oxygen Sensing, OXIDOREDUCTASE
Deposited on 2015-03-30, released 2016-01-13
The last revision prior to the SCOPe 2.06 freeze date was dated 2016-01-13, with a file datestamp of 2016-01-08.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hypoxia-inducible factor 1-alpha inhibitor
    Species: Homo sapiens [TaxId:9606]
    Gene: HIF1AN, FIH1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4z2wa_
  • Heterogens: AKG, PEG, FE, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4z2wA (A:)
gshmaataaeavasgsgepreeagalgpawdesqlrsysfptrpiprlsqsdpraeelie
neepvvltdtnlvypalkwdleylqenigngdfsvysasthkflyydekkmanfqnfkpr
snreemkfhefveklqdiqqrggeerlylqqtlndtvgrkivmdflgfnwnwinkqqgkr
gwgqltsnllligmegnvtpahydeqqnffaqikgykrcilfppdqfeclypypvhhpcd
rqsqvdfdnpdyerfpnfqnvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwy
kgaptpkrieyplkahqkvaimrniekmlgealgnpqevgpllntmikgryn

    Sequence, based on observed residues (ATOM records): (download) 
    >4z2wA (A:)
vasgsgepreeagalgpawdesqlrsysfptrpiprlsqsdpraeelieneepvvltdtn
lvypalkwdleylqenigngdfsvysasthkflyydekkmanfqnfkprsnreemkfhef
veklqdiqqrggeerlylqqtlndtvgrkivmdflgfnwnwinkqqgkrgwgqltsnlll
igmegnvtpahydeqqnffaqikgykrcilfppdqfeclypypvhhpcdrqsqvdfdnpd
yerfpnfqnvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwykgaptpkriey
plkahqkvaimrniekmlgealgnpqevgpllntmikgryn