PDB entry 4yxw

View 4yxw on RCSB PDB site
Description: Bovine heart mitochondrial F1-ATPase inhibited by AMP-PNP and ADP in the presence of thiophosphate.
Class: hydrolase
Keywords: hydrolase, complex, mitochondrial
Deposited on 2015-03-23, released 2015-05-06
The last revision prior to the SCOPe 2.05 freeze date was dated 2015-05-06, with a file datestamp of 2015-05-01.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP synthase subunit alpha, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19483 (Start-509)
      • variant (480)
    Domains in SCOPe 2.05: d4yxwa1, d4yxwa2, d4yxwa3
  • Chain 'B':
    Compound: ATP synthase subunit alpha, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19483 (Start-509)
      • variant (480)
    Domains in SCOPe 2.05: d4yxwb1, d4yxwb2, d4yxwb3
  • Chain 'C':
    Compound: ATP synthase subunit alpha, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19483 (Start-509)
      • variant (480)
    Domains in SCOPe 2.05: d4yxwc1, d4yxwc2, d4yxwc3
  • Chain 'D':
    Compound: ATP synthase subunit beta, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4yxwd1, d4yxwd2, d4yxwd3
  • Chain 'E':
    Compound: ATP synthase subunit beta, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4yxwe1, d4yxwe2, d4yxwe3
  • Chain 'F':
    Compound: ATP synthase subunit beta, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4yxwf1, d4yxwf2, d4yxwf3
  • Chain 'G':
    Compound: ATP synthase subunit gamma, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: ATP synthase subunit delta, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4yxwh1, d4yxwh2
  • Chain 'I':
    Compound: ATP synthase subunit epsilon, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4yxwi_
  • Heterogens: ANP, MG, CL, TS6, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4yxwA (A:)
ektgtaevssileerilgadtsvdleetgrvlsigdgiarvhglrnvqaeemvefssglk
gmslnlepdnvgvvvfgndklikegdivkrtgaivdvpvgeellgrvvdalgnaidgkgp
igskarrrvglkapgiiprisvrepmqtgikavdslvpigrgqreliigdrqtgktsiai
dtiinqkrfndgtdekkklyciyvaigqkrstvaqlvkrltdadamkytivvsatasdaa
plqylapysgcsmgeyfrdngkhaliiyddlskqavayrqmslllrrppgreaypgdvfy
lhsrlleraakmndafgggsltalpvietqagdvsayiptnvisitdgqifletelfykg
irpainvglsvsrvgsaaqtramkqvagtmklelaqyrevaafaqfgsdldaatqqllsr
gvrltellkqgqyspmaieeqvaviyagvrgyldklepskitkfenaflshvisqhqall
gkirtdgkiseesdaklkeivtnflagfea

    Sequence, based on observed residues (ATOM records): (download) 
    >4yxwA (A:)
svdleetgrvlsigdgiarvhglrnvqaeemvefssglkgmslnlepdnvgvvvfgndkl
ikegdivkrtgaivdvpvgeellgrvvdalgnaidgkgpigskarrrvglkapgiipris
vrepmqtgikavdslvpigrgqreliigdrqtgktsiaidtiinqkrfndgtdekkklyc
iyvaigqkrstvaqlvkrltdadamkytivvsatasdaaplqylapysgcsmgeyfrdng
khaliiyddlskqavayrqmslllrrppgreaypgdvfylhsrlleraakmndafgggsl
talpvietqagdvsayiptnvisitdgqifletelfykgirpainvglsvsrvgsaaqtr
amkqvagtmklelaqyrevaafaqfgsdldaatqqllsrgvrltellkqgqyspmaieeq
vaviyagvrgyldklepskitkfenaflshvisqhqallgkirtdgkiseesdaklkeiv
tnflagfea

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4yxwB (B:)
ektgtaevssileerilgadtsvdleetgrvlsigdgiarvhglrnvqaeemvefssglk
gmslnlepdnvgvvvfgndklikegdivkrtgaivdvpvgeellgrvvdalgnaidgkgp
igskarrrvglkapgiiprisvrepmqtgikavdslvpigrgqreliigdrqtgktsiai
dtiinqkrfndgtdekkklyciyvaigqkrstvaqlvkrltdadamkytivvsatasdaa
plqylapysgcsmgeyfrdngkhaliiyddlskqavayrqmslllrrppgreaypgdvfy
lhsrlleraakmndafgggsltalpvietqagdvsayiptnvisitdgqifletelfykg
irpainvglsvsrvgsaaqtramkqvagtmklelaqyrevaafaqfgsdldaatqqllsr
gvrltellkqgqyspmaieeqvaviyagvrgyldklepskitkfenaflshvisqhqall
gkirtdgkiseesdaklkeivtnflagfea

    Sequence, based on observed residues (ATOM records): (download) 
    >4yxwB (B:)
vdleetgrvlsigdgiarvhglrnvqaeemvefssglkgmslnlepdnvgvvvfgndkli
kegdivkrtgaivdvpvgeellgrvvdalgnaidgkgpigskarrrvglkapgiiprisv
repmqtgikavdslvpigrgqreliigdrqtgktsiaidtiinqkrfndgtdekkklyci
yvaigqkrstvaqlvkrltdadamkytivvsatasdaaplqylapysgcsmgeyfrdngk
haliiyddlskqavayrqmslllrrppgreaypgdvfylhsrlleraakmndafgggslt
alpvietqagdvsayiptnvisitdgqifletelfykgirpainvglsvsrvgsaaqtra
mkqvagtmklelaqyrevaldaatqqllsrgvrltellkqgqyspmaieeqvaviyagvr
gyldklepskitkfenaflshvisqhqallgkirtdgkiseesdaklkeivtnflagfea

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4yxwC (C:)
ektgtaevssileerilgadtsvdleetgrvlsigdgiarvhglrnvqaeemvefssglk
gmslnlepdnvgvvvfgndklikegdivkrtgaivdvpvgeellgrvvdalgnaidgkgp
igskarrrvglkapgiiprisvrepmqtgikavdslvpigrgqreliigdrqtgktsiai
dtiinqkrfndgtdekkklyciyvaigqkrstvaqlvkrltdadamkytivvsatasdaa
plqylapysgcsmgeyfrdngkhaliiyddlskqavayrqmslllrrppgreaypgdvfy
lhsrlleraakmndafgggsltalpvietqagdvsayiptnvisitdgqifletelfykg
irpainvglsvsrvgsaaqtramkqvagtmklelaqyrevaafaqfgsdldaatqqllsr
gvrltellkqgqyspmaieeqvaviyagvrgyldklepskitkfenaflshvisqhqall
gkirtdgkiseesdaklkeivtnflagfea

    Sequence, based on observed residues (ATOM records): (download) 
    >4yxwC (C:)
vdleetgrvlsigdgiarvhglrnvqaeemvefssglkgmslnlepdnvgvvvfgndkli
kegdivkrtgaivdvpvgeellgrvvdalgnaidgkgpigskarrrvglkapgiiprisv
repmqtgikavdslvpigrgqreliigdrqtgktsiaidtiinqkrfndgtdekkklyci
yvaigqkrstvaqlvkrltdadamkytivvsatasdaaplqylapysgcsmgeyfrdngk
haliiyddlskqavayrqmslllrrppgreaypgdvfylhsrlleraakmndafgggslt
alpvietqagdvsayiptnvisitdgqifletelfykgirpainvglsvsrvgsaaqtra
mkqvagtmklelaqyrevaafaqfgsdldaatqqllsrgvrltellkqgqyspmaieeqv
aviyagvrgyldklepskitkfenaflshvisqhqallgkirtdgkiseesdaklkeivt
nflagfea

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4yxwD (D:)
aaqaspspkagattgrivavigavvdvqfdeglppilnalevqgretrlvlevaqhlges
tvrtiamdgteglvrgqkvldsgapiripvgpetlgrimnvigepidergpiktkqfaai
haeapefvemsveqeilvtgikvvdllapyakggkiglfggagvgktvlimelinnvaka
hggysvfagvgertregndlyhemiesgvinlkdatskvalvygqmneppgararvaltg
ltvaeyfrdqegqdvllfidnifrftqagsevsallgripsavgyqptlatdmgtmqeri
tttkkgsitsvqaiyvpaddltdpapattfahldattvlsraiaelgiypavdpldstsr
imdpnivgsehydvargvqkilqdykslqdiiailgmdelseedkltvsrarkiqrflsq
pfqvaevftghlgklvplketikgfqqilageydhlpeqafymvgpieeavakadklaee
hs

    Sequence, based on observed residues (ATOM records): (download) 
    >4yxwD (D:)
ttgrivavigavvdvqfdeglppilnalevqgretrlvlevaqhlgestvrtiamdgteg
lvrgqkvldsgapiripvgpetlgrimnvigepidergpiktkqfaaihaeapefvemsv
eqeilvtgikvvdllapyakggkiglfggagvgktvlimelinnvakahggysvfagvge
rtregndlyhemiesgvinlkdatskvalvygqmneppgararvaltgltvaeyfrdqeg
qdvllfidnifrftqagsevsallgripsavgyqptlatdmgtmqeritttkkgsitsvq
aiyvpaddltdpapattfahldattvlsraiaelgiypavdpldstsrimdpnivgsehy
dvargvqkilqdykslqdiiailgmdelseedkltvsrarkiqrflsqpfqvaevftghl
gklvplketikgfqqilageydhlpeqafymvgpieeavakadklae

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4yxwE (E:)
aaqaspspkagattgrivavigavvdvqfdeglppilnalevqgretrlvlevaqhlges
tvrtiamdgteglvrgqkvldsgapiripvgpetlgrimnvigepidergpiktkqfaai
haeapefvemsveqeilvtgikvvdllapyakggkiglfggagvgktvlimelinnvaka
hggysvfagvgertregndlyhemiesgvinlkdatskvalvygqmneppgararvaltg
ltvaeyfrdqegqdvllfidnifrftqagsevsallgripsavgyqptlatdmgtmqeri
tttkkgsitsvqaiyvpaddltdpapattfahldattvlsraiaelgiypavdpldstsr
imdpnivgsehydvargvqkilqdykslqdiiailgmdelseedkltvsrarkiqrflsq
pfqvaevftghlgklvplketikgfqqilageydhlpeqafymvgpieeavakadklaee
hs

    Sequence, based on observed residues (ATOM records): (download) 
    >4yxwE (E:)
ttgrivavigavvdvqfdeglppilnalevqgretrlvlevaqhlgestvrtiamdgteg
lvrgqkvldsgapiripvgpetlgrimnvigepidergpiktkqfaaihaeapefvemsv
eqeilvtgikvvdllapyakggkiglfggagvgktvlimelinnvakahggysvfagvge
rtregndlyhemiesgvinlkdatskvalvygqmneppgararvaltgltvaeyfrdqeg
qdvllfidnifrftqagsevsallgripsavgyqptlatdmgtmqeritttkkgsitsvq
aiyvpaddltdpapattfahldattvlsraiaelgiypavdpldstsrimdpnivgsehy
dvargvqkilqdykslqdilseedkltvsrarkiqrflsqpfqvaevftghlgklvplke
tikgfqqilageydhlpeqafymvgpieeavakadkla

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4yxwF (F:)
aaqaspspkagattgrivavigavvdvqfdeglppilnalevqgretrlvlevaqhlges
tvrtiamdgteglvrgqkvldsgapiripvgpetlgrimnvigepidergpiktkqfaai
haeapefvemsveqeilvtgikvvdllapyakggkiglfggagvgktvlimelinnvaka
hggysvfagvgertregndlyhemiesgvinlkdatskvalvygqmneppgararvaltg
ltvaeyfrdqegqdvllfidnifrftqagsevsallgripsavgyqptlatdmgtmqeri
tttkkgsitsvqaiyvpaddltdpapattfahldattvlsraiaelgiypavdpldstsr
imdpnivgsehydvargvqkilqdykslqdiiailgmdelseedkltvsrarkiqrflsq
pfqvaevftghlgklvplketikgfqqilageydhlpeqafymvgpieeavakadklaee
hs

    Sequence, based on observed residues (ATOM records): (download) 
    >4yxwF (F:)
ttgrivavigavvdvqfdeglppilnalevqgretrlvlevaqhlgestvrtiamdgteg
lvrgqkvldsgapiripvgpetlgrimnvigepidergpiktkqfaaihaeapefvemsv
eqeilvtgikvvdllapyakggkiglfggagvgktvlimelinnvakahggysvfagvge
rtregndlyhemiesgvinlkdatskvalvygqmneppgararvaltgltvaeyfrdqeg
qdvllfidnifrftqagsevsallgripsavgyqptlatdmgtmqeritttkkgsitsvq
aiyvpaddltdpapattfahldattvlsraiaelgiypavdpldstsrimdpnivgsehy
dvargvqkilqdykslqdiiailgmdelseedkltvsrarkiqrflsqpfqvaevftghl
gklvplketikgfqqilageydhlpeqafymvgpieeavakadkla

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4yxwH (H:)
aeaaaaqapaagpgqmsftfasptqvffnsanvrqvdvptqtgafgilaahvptlqvlrp
glvvvhaedgttskyfvssgsvtvnadssvqllaeeavtldmldlgaakanlekaqsell
gaadeatraeiqirieanealvkale

    Sequence, based on observed residues (ATOM records): (download) 
    >4yxwH (H:)
qmsftfasptqvffnsanvrqvdvptqtgafgilaahvpvlrpglvvvhaedgttskyfv
ssgsvtvnadssvqllaeeavtldmldlgaakanlekaqsellgaadeatraeiqiriea
nealvkal

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >4yxwI (I:)
vaywrqaglsyirysqicakavrdalktefkanamktsgstikivkvkke

    Sequence, based on observed residues (ATOM records): (download) 
    >4yxwI (I:)
vaywrqaglsyirysqicakavrdalktefkanamktsgstikivkv