PDB entry 4yv1

View 4yv1 on RCSB PDB site
Description: Crystal structure of Trypanosoma cruzi spermidine synthase in complex with quinolin-8-yl piperidine-1-carboxylate
Class: transferase
Keywords: methyltransferase, polyamine synthesis, TRANSFERASE
Deposited on 2015-03-19, released 2015-09-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-02-05, with a file datestamp of 2020-01-31.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Spermidine synthase, putative
    Species: Trypanosoma cruzi (strain CL Brener) [TaxId:353153]
    Gene: Tc00.1047053510339.50
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4yv1a_
  • Chain 'B':
    Compound: Spermidine synthase, putative
    Species: Trypanosoma cruzi (strain CL Brener) [TaxId:353153]
    Gene: Tc00.1047053510339.50
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4yv1b_
  • Chain 'C':
    Compound: Spermidine synthase, putative
    Species: Trypanosoma cruzi (strain CL Brener) [TaxId:353153]
    Gene: Tc00.1047053510339.50
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4yv1c_
  • Chain 'D':
    Compound: Spermidine synthase, putative
    Species: Trypanosoma cruzi (strain CL Brener) [TaxId:353153]
    Gene: Tc00.1047053510339.50
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4yv1d_
  • Heterogens: S4M, 4K2, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4yv1A (A:)
mahhhhhhmpgselisggwfreendqwpgqamslrvekvlydaptkfqhltifesdpkgp
wgtvmaldgciqvtdydefvyhevlghtslcshpkpervliigggdggvlrevlrhgtve
hcdlvdidgevmeqskqhfpqisrsladpratvrvgdglafvrqtpdntydvviidttdp
agpasklfgeafykdvlrilkpdgiccnqgesiwldleliekmsrfiretgfasvqyalm
hvptypcgsigtlvcskkagvdvtkplrpvedmpfakdlkyydsemhkasfalprfarhi
nnse

    Sequence, based on observed residues (ATOM records): (download) 
    >4yv1A (A:)
gwfreendqwpgqamslrvekvlydaptkfqhltifesdpkgpwgtvmaldgciqvtdyd
efvyhevlghtslcshpkpervliigggdggvlrevlrhgtvehcdlvdidgevmeqskq
hfpqisrsladpratvrvgdglafvrqtpdntydvviidttafykdvlrilkpdgiccnq
gesiwldleliekmsrfiretgfasvqyalmhvptypcgsigtlvcskkagvdvtkplrp
vedmpfakdlkyydsemhkasfalprfarhinn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4yv1B (B:)
mahhhhhhmpgselisggwfreendqwpgqamslrvekvlydaptkfqhltifesdpkgp
wgtvmaldgciqvtdydefvyhevlghtslcshpkpervliigggdggvlrevlrhgtve
hcdlvdidgevmeqskqhfpqisrsladpratvrvgdglafvrqtpdntydvviidttdp
agpasklfgeafykdvlrilkpdgiccnqgesiwldleliekmsrfiretgfasvqyalm
hvptypcgsigtlvcskkagvdvtkplrpvedmpfakdlkyydsemhkasfalprfarhi
nnse

    Sequence, based on observed residues (ATOM records): (download) 
    >4yv1B (B:)
elisggwfreendqwpgqamslrvekvlydaptkfqhltifesdpkgpwgtvmaldgciq
vtdydefvyhevlghtslcshpkpervliigggdggvlrevlrhgtvehcdlvdidgevm
eqskqhfpqisrsladpratvrvgdglafvrqtpdntydvviidttdpagpasklfafyk
dvlrilkpdgiccnqgesiwldleliekmsrfiretgfasvqyalmhvptypcgsigtlv
cskkagvdvtkplrpvedmpfakdlkyydsemhkasfalprfarhinn

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4yv1C (C:)
mahhhhhhmpgselisggwfreendqwpgqamslrvekvlydaptkfqhltifesdpkgp
wgtvmaldgciqvtdydefvyhevlghtslcshpkpervliigggdggvlrevlrhgtve
hcdlvdidgevmeqskqhfpqisrsladpratvrvgdglafvrqtpdntydvviidttdp
agpasklfgeafykdvlrilkpdgiccnqgesiwldleliekmsrfiretgfasvqyalm
hvptypcgsigtlvcskkagvdvtkplrpvedmpfakdlkyydsemhkasfalprfarhi
nnse

    Sequence, based on observed residues (ATOM records): (download) 
    >4yv1C (C:)
sggwfreendqwpgqamslrvekvlydaptkfqhltifesdpkgpwgtvmaldgciqvtd
ydefvyhevlghtslcshpkpervliigggdggvlrevlrhgtvehcdlvdidgevmeqs
kqhfpqisrsladpratvrvgdglafvrqtpdntydvviidttafykdvlrilkpdgicc
nqgesiwldleliekmsrfiretgfasvqyalmhvptypcgsigtlvcskkagvdvtkpl
rpvedmpfakdlkyydsemhkasfalprfarhinn

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4yv1D (D:)
mahhhhhhmpgselisggwfreendqwpgqamslrvekvlydaptkfqhltifesdpkgp
wgtvmaldgciqvtdydefvyhevlghtslcshpkpervliigggdggvlrevlrhgtve
hcdlvdidgevmeqskqhfpqisrsladpratvrvgdglafvrqtpdntydvviidttdp
agpasklfgeafykdvlrilkpdgiccnqgesiwldleliekmsrfiretgfasvqyalm
hvptypcgsigtlvcskkagvdvtkplrpvedmpfakdlkyydsemhkasfalprfarhi
nnse

    Sequence, based on observed residues (ATOM records): (download) 
    >4yv1D (D:)
elisggwfreendqwpgqamslrvekvlydaptkfqhltifesdpkgpwgtvmaldgciq
vtdydefvyhevlghtslcshpkpervliigggdggvlrevlrhgtvehcdlvdidgevm
eqskqhfpqisrsladpratvrvgdglafvrqtpdntydvviidttdpagpasklfafyk
dvlrilkpdgiccnqgesiwldleliekmsrfiretgfasvqyalmhvptypcgsigtlv
cskkagvdvtkplrpvedmpfakdlkyydsemhkasfalprfarhinn