PDB entry 4yq2

View 4yq2 on RCSB PDB site
Description: Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
Class: transferase/transferase inhibitor
Keywords: TrmD, SAM-binding, knot, transferase-transferase inhibitor complex
Deposited on 2015-03-13, released 2016-03-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-03-16, with a file datestamp of 2016-03-11.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tRNA (guanine-N(1)-)-methyltransferase
    Species: Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [TaxId:71421]
    Gene: trmD, HI_0202
    Database cross-references and differences (RAF-indexed):
    • Uniprot P43912 (8-End)
      • expression tag (4-7)
    Domains in SCOPe 2.07: d4yq2a1, d4yq2a2
  • Heterogens: EFY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4yq2A (A:)
    glvprgshmwigvislfpemfkaitefgvtgravkhnllkvecwnprdftfdkhktvddr
    pygggpgmlmmvqplrdaihtakaaagegakviylspqgrkldqggvtelaqnqklilvc
    gryegiderliqteideewsigdyvltggelpamtlidavarfipgvlgkqasaeedsfa
    dglldcphytrpevlegltvppvlmsghheeirkwrlkqslqrtwlrrpelleglaltde
    qrkllkeaqaehns
    

    Sequence, based on observed residues (ATOM records): (download)
    >4yq2A (A:)
    rgshmwigvislfpemfkaitefgvtgravkhnllkvecwnprdftfdkhktvddrpygg
    gpgmlmmvqplrdaihtakaaagegakviylspqgrkldqggvtelaqnqklilvcgrye
    giderliqteideewsigdyvltggelpamtlidavarfipgvldglldcphytrpevle
    gltvppvlmsghheeirkwrlkqslqrtwlrrpelleglaltdeqrkllkeaqaeh