PDB entry 4yko
View 4yko on RCSB PDB site
Description: Crystal structure of the R111K:Y134F:T54V:R132Q:P39Q:R59Y:A32Y:F3Q mutant of human Cellular Retinoic Acid Binding Protein II with Retinal at 1.58 angstrom resolution
Class: transport protein
Keywords: Rhodopsin mimic, Photoswitchable protein, Retinal isomerization, Retinal PSB, Protein engineering, Retinal iminium pKa change by isomerization, transport protein
Deposited on
2015-03-04, released
2016-03-09
The last revision prior to the SCOPe 2.08 freeze date was dated
2016-08-03, with a file datestamp of
2016-07-29.
Experiment type: XRAY
Resolution: 1.57 Å
R-factor: N/A
AEROSPACI score: 0.45
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Cellular retinoic acid-binding protein 2
Species: Homo sapiens [TaxId:9606]
Gene: CRABP2
Database cross-references and differences (RAF-indexed):
- Uniprot P29373 (0-136)
- engineered mutation (2)
- engineered mutation (31)
- engineered mutation (38)
- engineered mutation (53)
- engineered mutation (58)
- engineered mutation (110)
- engineered mutation (131)
- engineered mutation (133)
Domains in SCOPe 2.08: d4ykoa_ - Chain 'B':
Compound: Cellular retinoic acid-binding protein 2
Species: Homo sapiens [TaxId:9606]
Gene: CRABP2
Database cross-references and differences (RAF-indexed):
- Uniprot P29373 (0-136)
- engineered mutation (2)
- engineered mutation (31)
- engineered mutation (38)
- engineered mutation (53)
- engineered mutation (58)
- engineered mutation (110)
- engineered mutation (131)
- engineered mutation (133)
Domains in SCOPe 2.08: d4ykob_ - Heterogens: RET, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>4ykoA (A:)
pnqsgnwkiirsenfeellkvlgvnvmlrkiyvaaaskqaveikqegdtfyikvsttvyt
teinfkvgeefeeqtvdgrpckslvkwesenkmvceqkllkgegpktswtkeltndgeli
ltmtaddvvctqvfvre
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>4ykoB (B:)
pnqsgnwkiirsenfeellkvlgvnvmlrkiyvaaaskqaveikqegdtfyikvsttvyt
teinfkvgeefeeqtvdgrpckslvkwesenkmvceqkllkgegpktswtkeltndgeli
ltmtaddvvctqvfvre