PDB entry 4yc3

View 4yc3 on RCSB PDB site
Description: CDK1/CyclinB1/CKS2 Apo
Class: cell cycle
Keywords: CDK1, Cyclin B1, CKS2, Cell cycle
Deposited on 2015-02-19, released 2016-04-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-08-30, with a file datestamp of 2017-08-25.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cyclin-dependent kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK1, CDC2, CDC28A, CDKN1, P34CDC2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06493 (5-301)
      • expression tag (4)
    Domains in SCOPe 2.08: d4yc3a1, d4yc3a2
  • Chain 'B':
    Compound: g2/mitotic-specific cyclin-b1
    Species: Homo sapiens [TaxId:9606]
    Gene: CCNB1, CCNB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14635
      • engineered mutation (6)
      • engineered mutation (77)
      • engineered mutation (189)
  • Chain 'C':
    Compound: Cyclin-dependent kinases regulatory subunit 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CKS2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4yc3c_
  • Heterogens: MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4yc3A (A:)
gplgsmedytkiekigegtygvvykgrhkttgqvvamkkirleseeegvpstaireisll
kelrhpnivslqdvlmqdsrlylifeflsmdlkkyldsippgqymdsslvksylyqilqg
ivfchsrrvlhrdlkpqnlliddkgtikladfglarafgipirvythevvtlwyrspevl
lgsarystpvdiwsigtifaelatkkplfhgdseidqlfrifralgtpnnevwpeveslq
dykntfpkwkpgslashvknldengldllskmliydpakrisgkmalnhpyfndldnqik
km

    Sequence, based on observed residues (ATOM records): (download) 
    >4yc3A (A:)
smedytkiekigegtygvvykgrhkttgqvvamkkirleseeegvpstaireisllkelr
hpnivslqdvlmqdsrlylifeflsmdlkkyldsippgqymdsslvksylyqilqgivfc
hsrrvlhrdlkpqnlliddkgtikladfglarafgipirvytvtlwyrspevllgsarys
tpvdiwsigtifaelatkkplfhgdseidqlfrifralgtpnnevwpeveslqdykntfp
kwkpgslashvknldengldllskmliydpakrisgkmalnhpyfndldnqikkm

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4yc3C (C:)
gplgsmahkqiyysdkyfdehyeyrhvmlprelskqvpkthlmseeewrrlgvqqslgwv
hymihepephillfrrplpkdqqk

    Sequence, based on observed residues (ATOM records): (download) 
    >4yc3C (C:)
kqiyysdkyfdehyeyrhvmlprelskqvpkthlmseeewrrlgvqqslgwvhymihepe
phillfrrplpk