PDB entry 4y2c

View 4y2c on RCSB PDB site
Description: M300V 3D polymerase mutant of EMCV
Class: viral protein
Keywords: RNA dependent RNA polymerase Cardiovirus Inhibitor resistance, viral protein
Deposited on 2015-02-09, released 2015-04-01
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-04-01, with a file datestamp of 2015-03-27.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Genome polyprotein
    Species: Mengo encephalomyocarditis virus [TaxId:12107]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12296 (0-459)
      • conflict (246)
      • engineered mutation (299)
    Domains in SCOPe 2.07: d4y2ca_
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4y2cA (A:)
galerlpdgprihvprktalrptvarqvfqpafapavlskfdprtdadvdevafskhtsn
qetlppvfrmvareyanrvfallgrdngrlsvkqaldglegmdpmdkntspglpyttlgm
rrtdvvdwetatlipfaaerlekmnnkdfsdivyqtflkdelrpiekvqaaktrivdvpp
fehcilgrqllgkfaskfqtqpglelgsaigcdpdvhwtafgvamqgfervydvdysnfd
sthsvamfrllaeeffseengfdplvkdyleslaiskhayeekrylitgglpsgcaatsv
lntimnniiiraglyltyknfefddvkvlsygddllvatnyqlnfdrvrtslaktgykit
panktstfplestledvvflkrkfkkegplyrpvmnrealeamlsyyrpgtlsekltsit
mlavhsgkqeydrlfapfrevgvivptfesveyrwrslfw