PDB entry 4xz0

View 4xz0 on RCSB PDB site
Description: ZAP-70-tSH2:compound-A complex
Class: Transferase/Transferase inhibitor
Keywords: Tyrosine kinase, cysteine adduct, Transferase-Transferase inhibitor complex
Deposited on 2015-02-03, released 2015-06-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-11, with a file datestamp of 2019-12-06.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tyrosine-protein kinase zap-70
    Species: Homo sapiens [TaxId:9606]
    Gene: ZAP70, SRK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P43403 (3-End)
      • expression tag (2)
    Domains in SCOPe 2.08: d4xz0a1, d4xz0a2, d4xz0a3
  • Heterogens: 4N5, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4xz0A (A:)
gphmpdpaahlpffygsisraeaeehlklagmadglfllrqclrslggyvlslvhdvrfh
hfpierqlngtyaiaggkahcgpaelcefysrdpdglpcnlrkpcnrpsglepqpgvfdc
lrdamvrdyvrqtwklegealeqaiisqapqvekliattahermpwyhssltreeaerkl
ysgaqtdgkfllrprkeqgtyalsliygktvyhylisqdkagkycipegtkfdtlwqlve
ylklkadgliyclkeacpnssa

    Sequence, based on observed residues (ATOM records): (download) 
    >4xz0A (A:)
hmpdpaahlpffygsisraeaeehlklagmadglfllrqclrslggyvlslvhdvrfhhf
pierqlngtyaiaggkahcgpaelcefysrdpdglpcnlrkpcnrpsglepqpgvfdclr
damvrdyvrqtwklegealeqaiisqapqvekliattahermpwyhssltreeaerklys
gaqtdgkfllrprkeqgtyalsliygktvyhylisqdkagkycipegtkfdtlwqlveyl
klkadgliyclkeacpns