PDB entry 4xse

View 4xse on RCSB PDB site
Description: Complex structure of thymidylate synthase from varicella zoster virus
Class: viral protein
Keywords: thymidylate synthase, herpesvirus, varicella zoster virus, vzv, viral protein
Deposited on 2015-01-22, released 2015-12-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-12-16, with a file datestamp of 2015-12-11.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: Varicella-zoster virus (strain Oka vaccine) [TaxId:341980]
    Gene: ORF13
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4xsea_
  • Chain 'B':
    Compound: Thymidylate synthase
    Species: Varicella-zoster virus (strain Oka vaccine) [TaxId:341980]
    Gene: ORF13
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4xseb_
  • Chain 'C':
    Compound: Thymidylate synthase
    Species: Varicella-zoster virus (strain Oka vaccine) [TaxId:341980]
    Gene: ORF13
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4xsec_
  • Chain 'D':
    Compound: Thymidylate synthase
    Species: Varicella-zoster virus (strain Oka vaccine) [TaxId:341980]
    Gene: ORF13
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4xsed_
  • Heterogens: PO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4xseA (A:)
mhhhhhhssgvdlgtenlyfqsmtkvpgftltgelqylkqvddilrygvrkrdrtgigtl
slfgmqarynlrnefpllttkrvfwravveellwfirgstdskelaakdihiwdiygssk
flnrngfhkrhtgdlgpiygfqwrhfgaeykdcqsnylqqgidqlqtvidtiktnpesrr
miisswnpkdiplmvlppchtlcqfyvangelscqvyqrsgdmglgvpfniagyalltyi
vahvtglktgdlihtmgdahiylnhidalkvqlarspkpfpclkiirnvtdindfkwddf
qldgynphppl

    Sequence, based on observed residues (ATOM records): (download) 
    >4xseA (A:)
tgelqylkqvddilrygvrkrdrtgigtlslfgmqarynlrnefpllttkrvfwravvee
llwfirgstdskelaakdihiwdiygsskflnrngfhkrhtgdlgpiygfqwrhfgaeyk
dcqsnylqqgidqlqtvidtiktnpesrrmiisswnpkdiplmvlppchtlcqfyvange
lscqvyqrsgdmglgvpfniagyalltyivahvtglktgdlihtmgdahiylnhidalkv
qlarspkpfpclkiirnvtdindfkwddfqldgynphpp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4xseB (B:)
mhhhhhhssgvdlgtenlyfqsmtkvpgftltgelqylkqvddilrygvrkrdrtgigtl
slfgmqarynlrnefpllttkrvfwravveellwfirgstdskelaakdihiwdiygssk
flnrngfhkrhtgdlgpiygfqwrhfgaeykdcqsnylqqgidqlqtvidtiktnpesrr
miisswnpkdiplmvlppchtlcqfyvangelscqvyqrsgdmglgvpfniagyalltyi
vahvtglktgdlihtmgdahiylnhidalkvqlarspkpfpclkiirnvtdindfkwddf
qldgynphppl

    Sequence, based on observed residues (ATOM records): (download) 
    >4xseB (B:)
gelqylkqvddilrygvrkrdrtgigtlslfgmqarynlrnefpllttkrvfwravveel
lwfirgstdskelaakdihiwdiygsskflnrngfhkrhtgdlgpiygfqwrhfgaeykd
cqsnylqqgidqlqtvidtiktnpesrrmiisswnpkdiplmvlppchtlcqfyvangel
scqvyqrsgdmglgvpfniagyalltyivahvtglktgdlihtmgdahiylnhidalkvq
larspkpfpclkiirnvtdindfkwddfqldgynphppl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4xseC (C:)
mhhhhhhssgvdlgtenlyfqsmtkvpgftltgelqylkqvddilrygvrkrdrtgigtl
slfgmqarynlrnefpllttkrvfwravveellwfirgstdskelaakdihiwdiygssk
flnrngfhkrhtgdlgpiygfqwrhfgaeykdcqsnylqqgidqlqtvidtiktnpesrr
miisswnpkdiplmvlppchtlcqfyvangelscqvyqrsgdmglgvpfniagyalltyi
vahvtglktgdlihtmgdahiylnhidalkvqlarspkpfpclkiirnvtdindfkwddf
qldgynphppl

    Sequence, based on observed residues (ATOM records): (download) 
    >4xseC (C:)
ltgelqylkqvddilrygvrkrdgigtlslfgmqarynlrnefpllttkrvfwravveel
lwfirgstdskelaakdihiwdiygsskflnrngfhkrhtgdlgpiygfqwrhfgaeykd
cqsnylqqgidqlqtvidtiktnpesrrmiisswnpkdiplmvlppchtlcqfyvangel
scqvyqrsgdmglgvpfniagyalltyivahvtglktgdlihtmgdahiylnhidalkvq
larspkpfpclkiirnvtdindfkwddfqldgynphppl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4xseD (D:)
mhhhhhhssgvdlgtenlyfqsmtkvpgftltgelqylkqvddilrygvrkrdrtgigtl
slfgmqarynlrnefpllttkrvfwravveellwfirgstdskelaakdihiwdiygssk
flnrngfhkrhtgdlgpiygfqwrhfgaeykdcqsnylqqgidqlqtvidtiktnpesrr
miisswnpkdiplmvlppchtlcqfyvangelscqvyqrsgdmglgvpfniagyalltyi
vahvtglktgdlihtmgdahiylnhidalkvqlarspkpfpclkiirnvtdindfkwddf
qldgynphppl

    Sequence, based on observed residues (ATOM records): (download) 
    >4xseD (D:)
tgelqylkqvddilrygvrkrdrtgigtlslfgmqarynlrnefpllttkrvfwravvee
llwfirgstdskelaakdihiwdiygsskflnrngfhkrhgdlgpiygfqwrhfgaeykd
cqsnylqqgidqlqtvidtiktnpesrrmiisswnpkdiplmvlppchtlcqfyvangel
scqvyqrsgdmglgvpfniagyalltyivahvtglktgdlihtmgdahiylnhidalkvq
larspkpfpclkiirnvtdindfkwddfqldgynphppl