PDB entry 4xrq

View 4xrq on RCSB PDB site
Description: Disulfide stabilized HIV-1 CA hexamer 4mut (S41A, Q67H, V165I, L172I) in complex with PF-3450074
Class: viral protein
Keywords: Viral protein, capsid, inhibitor
Deposited on 2015-01-21, released 2015-07-15
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-08-12, with a file datestamp of 2015-08-07.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: capsid protein p24
    Species: Human immunodeficiency virus type 1 group M subtype B (isolate NY5) [TaxId:11698]
    Gene: GAG
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12493 (0-End)
      • engineered mutation (13)
      • engineered mutation (40)
      • engineered mutation (44)
      • engineered mutation (66)
      • engineered mutation (164)
      • engineered mutation (171)
      • engineered mutation (184)
    Domains in SCOPe 2.06: d4xrqa1, d4xrqa2
  • Heterogens: 1B0, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4xrqA (A:)
pivqnlqgqmvhqcisprtlnawvkvveekafspevipmfaalscgatpqdlntmlntvg
ghqaamhmlketineeaaewdrlhpvhagpiapgqmreprgsdiagttstlqeqigwmth
nppipvgeiykrwiilglnkivrmysptsildirqgpkepfrdyidrfyktiraeqasqe
vknaatetllvqnanpdcktilkalgpgatleemmtacqgvggpghkarvl

    Sequence, based on observed residues (ATOM records): (download) 
    >4xrqA (A:)
pivqnlqgqmvhqcisprtlnawvkvveekafspevipmfaalscgatpqdlntmlntvg
ghqaamhmlketineeaaewdrlhpvhagpiapgqmreprgsdiagttstlqeqigwmth
nppipvgeiykrwiilglnkivrmysptsildirqgpkepfrdyidrfyktiraeqasqe
atetllvqnanpdcktilkalgpgatleemmtacq