PDB entry 4xph
View 4xph on RCSB PDB site
Description: X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) bound to 3,4dichlorophenethylamine
Class: protein transport/inhibitor
Keywords: integral membrane protein, neurotransmitter transporter, protein transport-inhibitor complex
Deposited on
2015-01-17, released
2015-05-06
The last revision prior to the SCOPe 2.06 freeze date was dated
2015-08-19, with a file datestamp of
2015-08-14.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.15
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transporter
Species: Drosophila melanogaster [TaxId:7227]
Gene: DAT, CG8380
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NB97 (0-533)
- engineered mutation (49)
- engineered mutation (96)
- engineered mutation (349)
- engineered mutation (360)
- Chain 'H':
Compound: Antibody fragment Heavy chain
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
- Chain 'L':
Compound: Antibody fragment Light chain
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d4xphl1, d4xphl2 - Heterogens: P4G, 42J, NA, CL, CLR, N9S, HOH