PDB entry 4xp9
View 4xp9 on RCSB PDB site
Description: X-ray structure of Drosophila dopamine transporter bound to psychostimulant D-amphetamine
Class: transport protein/inhibitor
Keywords: integral membrane protein, all-alpha helical antidepressant complex, membrane protein, protein transport, transport protein-inhibitor complex
Deposited on
2015-01-16, released
2015-05-06
The last revision prior to the SCOPe 2.06 freeze date was dated
2015-11-25, with a file datestamp of
2015-11-20.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.17
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'C':
Compound: Transporter
Species: Drosophila melanogaster [TaxId:7227]
Gene: DAT, CG8380, Dmel_CG8380
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0B4KEX2 (0-535)
- engineered mutation (49)
- engineered mutation (349)
- expression tag (536)
- Chain 'H':
Compound: antibody fragment light chain-protein, 9d5-light chain
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
- Chain 'L':
Compound: antibody fragment heavy chain-protein, 9d5-heavy chain
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d4xp9l1, d4xp9l2 - Heterogens: Y01, NAG, MAL, MPO, CLR, 1WE, P4G, NA, CL, HOH