PDB entry 4xm7

View 4xm7 on RCSB PDB site
Description: Anthrax toxin lethal factor with ligand-induced binding pocket
Class: toxin,hydrolase
Keywords: Anthrax toxin, lethal factor, metalloproteinase, metalloprotease, structural dynamics, ligand-induced conformational change, TOXIN, HYDROLASE
Deposited on 2015-01-14, released 2015-11-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-27, with a file datestamp of 2017-09-22.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lethal Factor
    Species: Bacillus anthracis [TaxId:1392]
    Gene: lef, pXO1-107, BXA0172, GBAA_pXO1_0172
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15917 (3-514)
      • engineered mutation (4)
      • expression tag (515)
    Domains in SCOPe 2.07: d4xm7a1, d4xm7a2, d4xm7a3
  • Heterogens: 41S, ZN, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4xm7A (A:)
snalsryekwekikqhyqhwsdslseegrgllkklqipiepkkddiihslsqeekellkr
iqidssdflsteekeflkklqidirdslseeekellnriqvdssnplsekekeflkklkl
diqpydinqrlqdtgglidspsinldvrkqykrdiqnidallhqsigstlynkiylyenm
ninnltatlgadlvdstdntkinrgifnefkknfkysissnymivdinerpaldnerlkw
riqlspdtragylengklilqrnigleikdvqiikqsekeyiridakvvpkskidtkiqe
aqlninqewnkalglpkytklitfnvhnryasnivesaylilnewknniqsdlikkvtny
lvdgngrfvftditlpniaeqythqdeiyeqvhskglyvpesrsillhgpskgvelrnds
egfihefghavddyagylldknqsdlvtnskkfidifkeegsnltsygrtneaeffaeaf
rlmhstdhaerlkvqknapktfqfindqikfiinslvpr

    Sequence, based on observed residues (ATOM records): (download) 
    >4xm7A (A:)
lsryekwekikqhyqhwsdslseegrgllkklqipiepkkddiihslsqeekellkriqi
dssdflsteekeflkklqidirdeeekellnriqvdssnplsekekeflkklkldiqpyd
inqrlqdtgglidspsinldvrkqykrdiqnidallhqsigstlynkiylyenmninnlt
atlgadlvdstdntkinrgifnefkknfkysissnymivdinerpaldnerlkwriqlsp
dtragylengklilqrnigleikdvqiikqsekeyiridakvvpkskidtkiqeaqlnin
qewnkalglpkytklitfnvhnryasnivesaylilnewknniqsdlikkvtnylvdgng
rfvftditlpniaeqythqdeiyeqvhskglyvpesrsillhgpskgvelrndsegfihe
fghavddyagylldknqsdlvtnskkfidifkeegsnltsygrtneaeffaeafrlmhst
dhaerlkvqknapktfqfindqikfiinsl