PDB entry 4xh9
View 4xh9 on RCSB PDB site
Description: crystal structure of human rhoa in complex with dh/ph fragment of the guanine nucleotide exchange factor net1
Class: signaling protein
Keywords: rhoa gtpase, signaling protein, activator, guanine nucleotide exchange factor
Deposited on
2015-01-05, released
2015-01-14
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-06-12, with a file datestamp of
2019-06-07.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Neuroepithelial cell-transforming gene 1 protein
Species: Homo sapiens [TaxId:9606]
Gene: NET1, ARHGEF8
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: transforming protein rhoa
Species: Homo sapiens [TaxId:9606]
Gene: RHOA, ARH12, ARHA, RHO12
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4xh9b_ - Chain 'D':
Compound: Neuroepithelial cell-transforming gene 1 protein
Species: Homo sapiens [TaxId:9606]
Gene: NET1, ARHGEF8
Database cross-references and differences (RAF-indexed):
- Chain 'E':
Compound: transforming protein rhoa
Species: Homo sapiens [TaxId:9606]
Gene: RHOA, ARH12, ARHA, RHO12
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4xh9e_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4xh9B (B:)
gaairkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdt
agqedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkd
lrndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalq
Sequence, based on observed residues (ATOM records): (download)
>4xh9B (B:)
airkklvivgdgacgktcllivnspevyvptvfenyvadievdgkqvelalwdtagqedy
drlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlrndeh
trrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalq
- Chain 'D':
No sequence available.
- Chain 'E':
Sequence, based on SEQRES records: (download)
>4xh9E (E:)
gaairkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdt
agqedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkd
lrndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalq
Sequence, based on observed residues (ATOM records): (download)
>4xh9E (E:)
airkklvivgdgacgktcllivnspevyvptvfenyvadievdgkqvelalwdtagqedy
drlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlrndeh
trrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalq