PDB entry 4x8t
View 4x8t on RCSB PDB site
Description: FACTOR VIIA IN COMPLEX WITH THE INHIBITOR 7-chloro-3,4-dihydroisoquinolin-1(2H)-one
Class: hydrolase/hydrolase inhibitor
Keywords: GLYCOPROTEIN, HYDROLASE, SERINE PROTEASE, PLASMA, BLOOD COAGULATION FACTOR, PROTEIN INHIBITOR COMPLEX, CALCIUM- BINDING, hydrolase-hydrolase inhibitor complex
Deposited on
2014-12-10, released
2015-03-25
The last revision prior to the SCOPe 2.06 freeze date was dated
2015-04-08, with a file datestamp of
2015-04-03.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'H':
Compound: Factor VIIa (Heavy Chain)
Species: Homo sapiens [TaxId:9606]
Gene: F7
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d4x8th_ - Chain 'L':
Compound: Factor VIIa (Light Chain)
Species: Homo sapiens [TaxId:9606]
Gene: F7
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d4x8tl_ - Heterogens: 3Z8, CA, SO4, GOL, HOH
PDB Chain Sequences:
- Chain 'H':
Sequence, based on SEQRES records: (download)
>4x8tH (H:)
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp
Sequence, based on observed residues (ATOM records): (download)
>4x8tH (H:)
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrspniteymfcagysdgs
kdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmrsepr
pgvllrapfp
- Chain 'L':
Sequence; same for both SEQRES and ATOM records: (download)
>4x8tL (L:)
icvnenggceqycsdhtgtkrscrchegyslladgvsctptveypcgkipilekr