PDB entry 4x6j
View 4x6j on RCSB PDB site
Description: Development of N-(Functionalized benzoyl)-homocycloleucyl-glycinonitriles as Potent Cathepsin K Inhibitors.
Class: hydrolase
Keywords: cathepsin K, inhibitor, HYDROLASE
Deposited on
2014-12-08, released
2015-09-09
The last revision prior to the SCOPe 2.08 freeze date was dated
2015-09-23, with a file datestamp of
2015-09-18.
Experiment type: XRAY
Resolution: 1.59 Å
R-factor: N/A
AEROSPACI score: 0.44
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: cathepsin k
Species: Homo sapiens [TaxId:9606]
Gene: CTSK, CTSO, CTSO2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4x6ja_ - Heterogens: GOL, CL, K, PGO, 3Y2, HOH